Applied Plant Science


The fluorescence spectroscopy would be one of the most powerful methods to approach the life sciences. Now, various colored fluorophores including green fluorescence protein are under the usage and the photons emitting from only single molecule can be detectable by the combination of light detecting system and high performed laser.
In our laboratory, the protein conformation, dynamics of internal motion and other characteristics close correlating with the function are under investigation using the advanced laser fluorescence spectroscopy. The rotational correlation time and motional freedom of fluorophore in protein are analyzed by the sub-picosecond laser based TCSPC system. Translational motion of protein is analyzed by the fluorescence correlational spectrophotometer. The correlation between the enzyme activity and structural fluctuation are investigated using single molecule FRET analyzer.
Would you join us to study the bio-molecular science?


Time-resolved fluorescence, Single molecule detection, RIPs, Pyruvate dehydrogenase complex.

Research Theme

  1. Structure, dynamics, function correlation of RIPs.
  2. Reaction and regulation mechanisms of enzyme at single molecular level.
  3. Hoffmeister effect on the protein structure and stability.


Etsuko NISHIMOTO  Ph.D., M.Sc.


Location6-10-1 Hakozaki Higashi-ku Fukuoka 812-8581 JAPAN
Laboratory of Applied Plant Science, Kyushu University
(Faculty of Agriculture Building 7, Hakozaki Campus)
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