センター 成果論文リスト



  • Bao, L., Inoue, N., Ishikawa, M., Gotoh, E., Teh, O.K., Higa, T., Morimoto, T., Ginanjar, E.F., Harashima, H., Noda, N., Watahiki, M., Hiwatashi, Y., Sekine, M., Hasebe, M., Wada, M., Fujita, T., (2022) “A PSTAIRE-type cyclin-dependent kinase controls light responses in land plants.” Sci. Adv. 8 (4), 1–12. LINK
  • Fujimura, Y., Watanabe, M., Morikawa-Ichinose, T., Fujino, K., Yamamoto, M., Nishioka, S., Inoue, C., Ogawa, F., Yonekura, M., Nakasone, A., Kumazoe, M., Tachibana, H., (2022) “Metabolic Profiling for Evaluating the Dipeptidyl Peptidase-IV Inhibitory Potency of Diverse Green Tea Cultivars and Determining Bioactivity-Related Ingredients and Combinations.” J. Agric. Food Chem. 70 (21), 6455–6466. LINK
  • Hiasa, R., Kakimoto, K. ichi, Takegawa, K., Higuchi, Y., (2022) “Involvement of AAA ATPase AipA in endocytosis of the arginine permease AoCan1 depending on AoAbp1 in Aspergillus oryzae.” Fungal Biol.126 (2), 149–161. LINK
  • Ichinose, H., Ukeba, S., Kitaoka, T., (2022) “Latent potentials of the white-rot basidiomycete Phanerochaete chrysosporium responsible for sesquiterpene metabolism: CYP5158A1 and CYP5144C8 decorate (E)-α-bisabolene.” Enzyme Microb. Technol. 158 (March), 110037. LINK
  • Inoue, T., Funatsu, Y., Ohnishi, M., Isogawa, M., Kawashima, K., Tanaka, M., Moriya, K., Kawaratani, H., Momoda, R., Iio, E., Nakagawa, H., Suzuki, Y., Matsuura, K., Fujiwara, K., Nakajima, A., Yoshiji, H., Nakayama, J., Tanaka, Y., (2022) “Bile acid dysmetabolism in the gut-microbiota-liver axis under hepatitis C virus infection.” Liver Int. 42 (1), 124–134. LINK
  • Ito, K., Ito, D., Goto, M., Suzuki, S., Masuda, S., Iba, K., Kusumi, K., (2022) “Regulation of ppGpp Synthesis and Its Impact on Chloroplast Biogenesis during Early Leaf Development in Rice.” Plant Cell Physiol. 2 (April), 1–13. LINK
  • Li, Q., Hatakeyama, M., Kitaoka, T., (2022) “Bioadaptive Porous 3D Scaffolds Comprising Cellulose and Chitosan Nanofibers Constructed by Pickering Emulsion Templating.” Adv. Funct. Mater. 32 (22). LINK
  • Masato Hino, Tsuneyuki Tatsuke, Akihiro Morio, Hiroaki Mon, Jae Man Lee, Akitsu Masuda, Kohei Kakino, Yoshino Tonooka, T.K., (2022) “Characterization of a Novel Heterochromatin Protein 1 Homolog “ HP1c ”in the Silkworm, Bombyx mori.” 13 (7), 631-643. LINK
  • Permana, D., Niesel, K., Ford, M.J., Ichinose, H., (2022) “Latent Functions and Applications of Cytochrome P450 Monooxygenases from Thamnidium elegans: A Novel Biocatalyst for 14α-Hydroxylation of Testosterone.” ACS Omega 2022 (7), 13932–13941. LINK
  • Shirouchi, B., Fukuda, A., Akasaka, T., (2022) “Unlike Glycerophosphocholine or Choline Chloride , Dietary Phosphatidylcholine Does Not Increase Plasma Trimethylamine-N-Oxide Levels in Sprague-Dawley Rats.” Metabolites 12 (1), 64. LINK
  • Tokunaga, K., Akimoto, S., Aiba, M., Nakagomi, M., Suzuki, T., Tatsumi, R., Nakamura, M., (2022) “Connexin 43 is Localized in Gizzard Smooth Muscle Cells during Chicken Development.” J. Poult. Sci. LINK
  • Yamaguchi, A., Tsunematsu, T., Motojima, Y., Toriyama, K., Horinouchi, A., Ishii, Y., Murata, H., Yoshikawa, S., Nyuji, M., Shimizu, A., (2022) “Pituitary luteinizing hormone synthesis starts in aromatase ( cyp19a1b )‑ positive cells expressing esr1 and esr2b at the onset of puberty in Takifugu rubripes ( fugu ).” Cell Tissue Res. LINK
  • 今田舜介, 伊藤玲央, 徳重典英, 中野文尊, 中村涼, 橋爪拓斗, (2022) “ツブヒゲナガゾウムシ (コウチュウ目: ヒゲナガゾウムシ科: ノミヒゲナガゾウムシ亜科 ) の新産地ならびに生態的知見.” Fauna Ryukyuana 64, 23–26


  • Abe, K., Yamashita, S., Kitazaki, K., Katakura, Y., (2021) “Homogenization in water improves the recovery rate of imidazole dipeptides in meat.” Food Sci. Technol. Res. 27 (2), 335–339. LINK
  • Fukuda N.,Hatakeyama M.,Kitaoka T., (2021) “Enzymatic preparation and characterization of spherical microparticles composed of artificial lignin and tempo-oxidized cellulose nanofiber.” Nanomaterials 11 (4). LINK
  • Hahm T.H.,Tanaka M.,Nguyen H.N.,Tsutsumi A.,Aizawa K.,Matsui T., (2021) “Matrix-assisted laser desorption/ionization mass spectrometry-guided visualization analysis of intestinal absorption of acylated anthocyanins in Sprague-Dawley rats.” Food Chem. 334 (May 2020), 127586. LINK
  • Inoue, S., Nomura, S., (2021) “Two new species of Pseudophanias Raffray from Myanmar (Coleoptera: Staphylinidae: Pselaphinae).” Zootaxa 4996 (3), 591–599. LINK
  • Inoue, T., Funatsu, Y., Ohnishi, M., Isogawa, M., Kawashima, K., Tanaka, M., Moriya, K., Kawaratani, H., Momoda, R., Iio, E., Nakagawa, H., Suzuki, Y., Matsuura, K., Fujiwara, K., Nakajima, A., Yoshiji, H., Nakayama, J., Tanaka, Y., (2021) “Bile acid dysmetabolism in the gut‐microbiota‐liver axis under hepatitis C virus infection.” Liver Int. (August), 1–11. LINK
  • Maruyama-Nakashita, A., Ishibashi, Y., Yamamoto, K., Zhang, L., Morikawa-Ichinose, T., Kim, S.J., Hayashi, N., (2021) “Oxygen plasma modulates glucosinolate levels without affecting lipid contents and composition in Brassica napus seeds.” Biosci. Biotechnol. Biochem. 85 (12), 2434–2441. LINK
  • Nguele, R., Hirota, H., Sugai, Y., Sasaki, K., (2021) “Role of Polymer-Based Nanofluids on Asphaltene Adsorption during Carbon Dioxide (CO2 ) Injection.” Energy & Fuels. LINK
  • Obata, T., Kobayashi, K., Tadakuma, R., Akasaka, T., Iba, K., Negi, J., (2021) “The endoplasmic reticulum pathway for membrane lipid synthesis has a significant contribution toward shoot removal-induced root chloroplast development in arabidopsis.” Plant Cell Physiol. 62 (3), 494–501. LINK
  • Onizuka, S., Tanaka, M., Mishima, R., Nakayama, J., (2021) “Cultivation of spore-forming gut microbes using a combination of bile acids and amino acids.” Microorganisms 9 (8). LINK
  • Takeyama, A., Teramoto, A., Wang, T., Hayashi, T., Tanaka, Y., Sato, M., Shirouchi, B., (2021) “Dietary lysophospholipids reduce lymphatic cholesterol transport compared with dietary phospholipids in thoracic lymph-duct cannulated rats.” Lipids 56 (6), 579–590. LINK
  • Terada, M., Ide, S., Naito, T., Kimura, N., Matsusaki, M., Kaji, N., (2021) “Label-Free Cancer Stem-like Cell Assay Conducted at a Single Cell Level Using Microfluidic Mechanotyping Devices.” Anal. Chem. 93 (43), 14409–14416. LINK
  • Therdtatha, P., Song, Y., Tanaka, M., Mariyatun, M., Almunifah, M., Manurung, N.E.P., Indriarsih, S., Lu, Y., Nagata, K., Fukami, K., Ikeda, T., Lee, Y.K., Rahayu, E.S., Nakayama, J., (2021) “Gut microbiome of indonesian adults associated with obesity and type 2 diabetes: A cross-sectional study in an asian city, yogyakarta.” Microorganisms 9 (5), 1–19. LINK
  • Tsuji T.,Tsuboi K.,Yokota S.,Tagawa S.,Kondo T., (2021) “Characterization of an Amphiphilic Janus-Type Surface in the Cellulose Nanofibril Prepared by Aqueous Counter Collision.” Biomacromolecules 22 (2), 620–628. LINK
  • Watanabe, M., Sianoya, A., Mishima, R., Therdtatha, P., Rodriguez, A., Ramos, D.C., Lee, Y.K., Dalmacio, L.M., Nakayama, J., (2021) “Gut microbiome status of urban and rural Filipino adults in relation to diet and metabolic disorders.” FEMS Microbiol. Lett. 368 (20), 1–9. LINK
  • Yukawa, J., Kim, W., Nishino, T., Minami, T., Yamauchi, S., Ogawa, M., Ohara, K., (2021) “A new and a described species of Cystiphora (Diptera: Cecidomyiidae) from Japan, with reference to geographically diversified intraspecific populations of C. taraxaci and its host range expansion from native Japanese to alien and hybrid species of Taraxacum (Asteraceae).” Entomol. Sci. 24 (3), 284–301. LINK


  • INOUE, S., MARUYAMA, M., NOMURA, S., (2020) “Discovery of Tmesiphoromimus Löbl, 1964 (Coleoptera: Staphylinidae: Pselaphinae) from Japan, with Description of a New Species.” Japanese J. Entomol. 26 (1), 87–92
  • Inoue, S., Nomura, S., Yin, Z.W., (2020) “Three new species of Pseudophanias raffray from Japan and Taiwan island, and synonymy of Chandleriella hlaváč with Pseudophanias (Coleoptera, staphylinidae, pselaphinae).” Zookeys 2020 (987), 135–156. LINK
  • Ishishita K.,Higa T.,Tanaka H.,Inoue S.I.,Chung A.,Ushijima T.,Matsushita T.,Kinoshita T.,Nakai M.,Wada M.,Suetsugu N.,Gotoh E., (2020) “Phototropin2 contributes to the chloroplast avoidance response at the chloroplast-plasma membrane InterfAce.” Plant Physiol. 183 (5), 304–316. LINK
  • Kaneko T.,Toh S.,Mochida I.,Iwamori N.,Inai T.,Iida H., (2020) “Identification of TMCO2 as an acrosome-associated protein during rat spermiogenesis.” Mol. Reprod. Dev. 87 (7), 808–818. LINK
  • Kihara M.,Ushijima T.,Yamagata Y.,Tsuruda Y.,Higa T.,Abiko T.,Kubo T.,Wada M.,Suetsugu N.,Gotoh E., (2020) “Light-induced chloroplast movements in Oryza species.” J. Plant Res. 133 (4), 525–535. LINK
  • Oda Y.,Asatsuma S.,Nakasone H.,Matsuoka K., (2020) “Sucrose starvation induces the degradation of proteins in trans-Golgi network and secretory vesicle cluster in tobacco BY-2 cells.” Biosci. Biotechnol. Biochem. 84 (8), 1652–1666. LINK
  • Tanaka, M., Onizuka, S., Mishima, R., Nakayama, J., (2020) “Cultural isolation of spore-forming bacteria in human feces using bile acids.” Sci. Rep. 10 (1). LINK
  • Tanaka, M., Sanefuji, M., Morokuma, S., Yoden, M., Momoda, R., Sonomoto, K., Ogawa, M., Kato, K., Nakayama, J., (2020) “The association between gut microbiota development and maturation of intestinal bile acid metabolism in the first 3 y of healthy Japanese infants.” Gut Microbes 11 (2), 205–216. LINK
  • Zhang L.,Kawaguchi R.,Morikawa-ichinose T.,Allahham A.,Maruyama-nakashita A.,Kim S., (2020) “Sulfur Deficiency-Induced Glucosinolate Catabolism Attributed to Two β-Glucosidases, BGLU28 and BGLU30, is Required for Plant Growth Maintenance under Sulfur Deficiency.” Plant Cell Physiol. LINK


  • Ashour A.,Amen Y.,Allam A.E.,Kudo T.,Nagata M.,Ohnuki K.,Shimizu K., (2019) “New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus.” Phytochem. Lett. 32 (April), 10–14. LINK
  • Kaneko T.,Minohara T.,Shima S.,Yoshida K.,Fukuda A.,Iwamori N.,Inai T.,Iida H., (2019) “A membrane protein, TMCO5A, has a close relationship with manchette microtubules in rat spermatids during spermiogenesis.” Mol. Reprod. Dev. 86 (3), 330 – 341. LINK
  • Miyazaki Y.,Iwaihara Y.,Bak J.,Nakano H.,Takeuchi S.,Takeuchi H.,Matsui T.,Tachikawa D., (2019) “The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon okamuranus and β-glucan derived from Saccharomyces cerevisiae.” Biochem. Biophys. Res. Commun. 516 (1), 245 – 250. LINK
  • Satria D.,Tamrakar S.,Suhara H.,Kaneko S.,Shimizu K., (2019) “Mass Spectrometry-Based Untargeted Metabolomics and α-Glucosidase Inhibitory Activity of Lingzhi (Ganoderma lingzhi) During the Developmental Stages.” Molecules 24 (11), 1 – 14. LINK
  • Sugihara Y.,Onoue S.,Tashiro K.,Sato M.,Hasegawa T.,Katakura Y., (2019) “Carnosine induces intestinal cells to secrete exosomes that activate neuronal cells.” PLoS One 14 (5), 1–17. LINK
  • Tsuji, K., Yoon, K.S., Ogo, S., (2019) “Glyceraldehyde-3-phosphate dehydrogenase from Citrobacter sp. S-77 is post-translationally modified by CoA (protein CoAlation) under oxidative stress.” FEBS Open Bio 9 (1), 53–73. LINK
  • Yukawa J.,Harris K.M.,Kim W., (2019) “Descriptions of two new species of the genus Lasioptera(Diptera: Cecidomyiidae) that infest tomato in the Mediterranean Region and Hokkaido, Japan.” Appl. Entomol. Zool. LINK


  • Gotoh E.,Suetsugu N.,Higa T.,Matsushita T.,Tsukaya H.,Wada M., (2018) “Palisade cell shape affects the light-induced chloroplast movements and leaf photosynthesis.” Sci. Rep. 8 (1), 1 – 9. LINK
  • Honda M.,Muta A.,Shimazaki A.,Akasaka T.,Yoshikuni M.,Shimasaki Y.,Oshima Y., (2018) “High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes: a laboratory exposure study.” Environ. Sci. Pollut. Res. 25 (2), 1551 – 1558. LINK
  • Nakagawa, T., Zhu, Q., Tamrakar, S., Amen, Y., Mori, Y., Suhara, H., Kaneko, S., Kawashima, H., Okuzono, K., Inoue, Y., Ohnuki, K., Shimizu, K., (2018) “Changes in content of triterpenoids and polysaccharides in Ganoderma lingzhi at different growth stages.” J. Nat. Med. 72 (3), 734–744. LINK
  • Okino N.,Wakisaka H.,Ishibashi Y.,Ito M., (2018) “Visualization of Endoplasmic Reticulum and Mitochondria in Aurantiochytrium limacinum by the Expression of EGFP with Cell Organelle-Specific Targeting/Retaining Signals.” Mar. Biotechnol. 20 (2), 182 – 192. LINK
  • Tagawa S.,Kondo T., (2018) “Secretion of a callose hollow fiber from herbaceous plant protoplasts induced by inhibition of cell wall formation.” J. Wood Sci. 64 (5), 467 – 476. LINK


  • Hiraki E.,Furuta S.,Kuwahara R.,Takemoto N.,Nagata T.,Akasaka T.,Shirouchi B.,Sato M.,Ohnuki K.,Shimizu K., (2017) “Anti-obesity activity of Yamabushitake (Hericium erinaceus) powder in ovariectomized mice, and its potentially active compounds Eri.” J. Nat. Med. 71 (3), 482 – 491. LINK
  • Iiyama K.,Morishita M.,Lee J.M.,Mon H.,Kusakabe T.,Tashiro K.,Akasaka T.,Yasunaga-Aoki C.,Miyamoto K., (2017) “A reconsideration of the taxonomic position of two bacterial strains isolated from Flacherie-Diseased silkworms in 1965.” J. Insect Biotechnol. Sericology 86 (2), 35 – 41. LINK
  • Komiya Y.,Sawano S.,Mashima D.,Ichitsubo R.,Nakamura M.,Tatsumi R.,Ikeuchi Y.,Mizunoya W., (2017) “Mouse soleus (slow) muscle shows greater intramyocellular lipid droplet accumulation than EDL (fast) muscle: fiber type-specific analysis.” J. Muscle Res. Cell Motil. 38 (2), 163 – 173. LINK
  • Poudel P.,Tashiro Y.,Miyamoto Hirokuni,Miyamoto Hisashi,Okugawa Y.,Sakai K., (2017) “Development of a systematic feedback isolation approach for targeted strains from mixed culture systems.” J. Biosci. Bioeng. 123 (1), 63 – 70. LINK
  • Satone H.,Nonaka S.,Lee J.M.,Shimasaki Y.,Kusakabe T.,Kawabata S. ichiro,Oshima Y., (2017) “Tetrodotoxin- and tributyltin-binding abilities of recombinant pufferfish saxitoxin and tetrodotoxin binding proteins of Takifugu rubripes.” Toxicon 125, 50 – 52. LINK
  • Tanaka, M., Korenori, Y., Washio, M., Kobayashi, T., Momoda, R., Kiyohara, C., Kuroda, A., Saito, Y., Sonomoto, K., Nakayama, J., (2017) “Signatures in the gut microbiota of Japanese infants who developed food allergies in early childhood.” FEMS Microbiol. Ecol. 93 (8), 1–11. LINK
  • Togo Y.,Higuchi Y.,Katakura Y.,Takegawa K., (2017) “Early endosome motility mediates α-amylase production and cell differentiation in Aspergillus oryzae.” Sci. Rep. 7 (1), 15757. LINK


  • Amen, Y.M., Zhu, Q., Tran, H.B., Afifi, M.S., Halim, A.F., Ashour, A., Mira, A., Shimizu, K., (2016) “Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells.” J. Nat. Med.70 (3), 661–666. LINK
  • Tamrakar S.,Tran H.B.,Nishida M.,Kaifuchi S.,Suhara H.,Doi K.,Fukami K.,Parajuli G.P.,Shimizu K., (2016) “Antioxidative activities of 62 wild mushrooms from Nepal and the phenolic profile of some selected species.” J. Nat. Med. 70 (4), 769 – 779. LINK
  • Zhu, Q., Kakino, K., Nogami, C., Ohnuki, K., Shimizu, K., (2016) “An LC-MS/MS-SRM Method for Simultaneous Quantification of Four Representative Organosulfur Compounds in Garlic Products.” Food Anal. Methods 9 (12), 3378–3384. LINK
  • Masaki S.,Shiotsu H.,Ohnuki T.,Sakamoto F.,Utsunomiya S., (2015) “Effects of CeO2 nanoparticles on microbial metabolism.” Chem. Geol. 391, 33 – 41. LINK
  • Masuda A.,Xu J.,Mitsudome T.,Nagata Y.,Morokuma D.,Mon H.,Banno Y.,Kusakabe T.,Lee J.M., (2015) “Mass Production of an Active Peptide-N-Glycosidase F Using Silkworm-Baculovirus Expression System.” Mol. Biotechnol. 57 (8), 735 – 745. LINK
  • Morokuma D.,Mon H.,Banno Y.,Kusakabe T.,Lee J.M., (2015) “Differential N-Glycan modifications of human alpha 1-acid glycoprotein (α1AGP) produced in different silkworm strains using the baculovirus expression system.” J. Insect Biotechnol. Sericology 84 (2), 49 – 53. LINK
  • Morokuma D.,Xu J.,Mon H.,Hirata K.,Hino M.,Kuboe S.,Yamashita M.,Kusakabe T.,Lee J.M., (2015) “Human alpha 1-acid glycoprotein as a model protein for glycoanalysis in baculovirus expression vector system.” J. Asia. Pac. Entomol. 18 (2), 303 – 309. LINK
  • Zhu Q.,Nakagawa T.,Kishikawa A.,Ohnuki K.,Shimizu K., (2015) “In vitro bioactivities and phytochemical profile of various parts of the strawberry (Fragaria x ananassa var. Amaou).” J. Funct. Foods 13, 38 – 49. LINK
  • Honda M.,Muta A.,Akasaka T.,Inoue Y.,Shimasaki Y.,Kannan K.,Okino N.,Oshima Y., (2014) “Identification of perfluorooctane sulfonate binding protein in the plasma of tiger pufferfish Takifugu rubripes.” Ecotoxicol. Environ. Saf. 104 (1), 409 – 413. LINK
  • Taira E.,Iiyama K.,Mon H.,Mori K.,Akasaka T.,Tashiro K.,Yasunaga-Aoki C.,Lee J.M.,Kusakabe T., (2014) “Draft Genome Sequence of Entomopathogenic Serratia liquefaciens Strain FK01.” Genome Announc. 2 (3), 2014. LINK
  • Tan H.,Furuta S.,Nagata T.,Ohnuki K.,Akasaka T.,Shirouchi B.,Sato M.,Kondo R.,Shimizu K., (2014) “Inhibitory effects of the leaves of loquat (eriobotrya japonica) on bone mineral density loss in ovariectomized mice and osteoclast differentiation.” J. Agric. Food Chem. 62 (4), 836 – 841. LINK
  • Tanaka A.,Zhu Q.,Tan H.,Horiba H.,Ohnuki K.,Mori Y.,Yamauchi R.,Ishikawa H.,Iwamoto A.,Kawahara H.,Shimizu K., (2014) “Biological activities and phytochemical profiles of extracts from different parts of bamboo (phyllostachys pubescens).” Molecules 19 (6), 8238 – 8260. LINK
  • Tasaki M.,Asatsuma S.,Matsuoka K., (2014) “Monitoring protein turnover during phosphate starvation-dependent autophagic degradation using a photoconvertible fluorescent protein aggregate in tobacco BY-2 cells.” Front. Plant Sci. 5 (APR), 1 – 9. LINK
  • Tran H.B.,Yamamoto A.,Matsumoto S.,Ito H.,Igami K.,Miyazaki T.,Kondo R.,Shimizu K., (2014) “Hypotensive effects and angiotensin-converting enzyme inhibitory peptides of reishi (Ganoderma lingzhi) auto-digested extract.” Molecules 19 (9), 13473 – 13485. LINK
  • Yamashita Y.,Naraoka H., (2014) “Two homologous series of alkylpyridines in the Murchison meteorite.” Geochem. J. 48 (6), 519 – 525. LINK
  • 島崎晃成,本田匡人,赤坂泰輝,牟田朱美,鵜木(加藤)陽子,沖野望,島崎洋平,大嶋雄治, (2014) “ラット血漿におけるペルフルオロオクタンスルホン酸結合タンパク質の探索.” Japanese J. Environ. Toxicol.17 (1), 11 – 17. LINK