メラトニン受容体MT1が複数の細胞内シグナルを使い分けるしくみを解明した論文がNature Communicationsに掲載されました。

Nature Communications DOI：10.1038/s41467-026-73555-6
Structural basis and physiological significance of non-canonical Gs coupling to the melatonin MT1 receptor

Atsuro Oishi, Hiroyuki H. Okamoto, Keisuke Ikegami, Ronan McHugh, Bernard Masri, Tsukasa Kusakizako, Kazuhiro Kobayashi, Akifumi Takaki, Angeliki Karamitri, Erika Cecon, Julie Dam, Miki Nagase, Irina G. Tikhonova, Osamu Nureki & Ralf Jockers

Nature Communications (Published: 21 May 2026)