2014	2013	2012	2011	2010	2009	2008	2007
2006	2005	2004	2003	2002	2001	2000

最新はこちら

2011年
Kim, Y.H., Ida, M., Yamashita, S., Tsukamoto, S., Kumazoe,M., Sumida, M., Mitsuo Kawakami, M., Yamada, K., and Tachibana, H.,Anti-allergic effects of Kakrol (Momordica diocia Roxb.) flesh extract,Bioscience of Microbiota, Food and Health,31,1-6 ,2012.01.

Fujimura, Y., Kurihara, K., Ida, M., Kosaka, R., Miura, D., Wariishi, H., Maeda-Yamamoto, M., Nesumi, A., Saito, T., Kanda, T., Yamada, K., and Tachibana, H.,Metabolomics-Driven Nutraceutical Evaluation of Diverse Green Tea Cultivars,PLoS ONE,585, e23426,6(8),2011.05.

Byun, E.-H., Omura, T., Yamada, K., and Tachibana, H. ,Green tea polyphenol epigallocatechin-3-gallate inhibites TLR2 signaling induced by peptidoglycan through the polyphenol sensing molecule 67-kDa laminin receptor.,FEBS Lett.,585,814-820,2011.03.

2010年

Byun E-H., Fujimura Y., Yamada K., and Tachibana H.
TLR 4 signaling inhibitory pathway induced by green tea polyphenol epigallocatechin-3-gallate through 67-kDa laminin receptor.
J. Immunol., 185, 33-45 (2010)

Yamashita S., Yamashita T., Yamada K., and Tachibana H.
Flavones suppress type I IL-4 receptor signaling by down-regulating the expression of common gamma chain.
FEBS Lett. 584, 775-779 (2010)

Kurita I., Maeda-Yamamoto M., Tachibana. H., and Kamei M.
Antihypertensive effect of Benifuuki tea containing O-methylated EGCG.
J. Agric. Food Chem., 58, 1903-1908 (2010)

Lee JH., Kishikawa M., Kumazoe M., Yamada K., and Tachibana H.
Vitamin A enhances antitumor effect of a green tea polyphenol on melanoma by upregulating the polyphenol sensing molecule 67-kDa Laminin Receptor.
PLoS ONE, 5(6), e11051 (2010)

Kurihara K., Nagatomo S., Maeda-Yamamoto M., Yamada K., and Tachibana H.
Inhibitory effect on thrombin-induced myosin light chain phosphorylation by an extract of new green tea cultivar in A7r5 rat aortic smooth muscle cells.
Food Sci. Tech. Res. 16(3), 263-266 (2010)

Tanaka H., Yamanouchi M., Miyoshi H., Hirotsu K., Tachibana H., and Takahashi T.
Solid-phase synthesis of a combinatorial methylated epigallocatechin gallate library and their growth inhibitory effects on melanoma B16 cells.
Chem. Asian J., in press

Miura D., Fujimura Y., Tachibana H., and Wariishi H.
Highly Sensitive MALDI-Mass Spectrometry for High-throughput Metabolic Profiling.
Anal. Chem., 82, 498-504 (2010)

Kanouchi H., Shibuya M., Tsukamoto S., Fujimura Y., Tachibana H., Yamada K.,and Oka T.
Comparisons of uptake and cell surface binding among pyridoxal, pyridoxine and pyridoxamine in RAW264.7 cells.
Nutrition. 6(6), 648-652 (2010)

立花宏文
緑茶カテキンを感知するメカニズム
バイオチップ実用化ハンドブック, NTS, 340-345 (2010)

2009年

Yano S, Umeda D, Yamashita S, Yamada K, and Tachibana H.
Dietary apigenin attenuates the development of atopic dermatitis-like skin lesions in NC/Nga mice.
J. Nutr. Biochem., 20, 876-881 (2009)

Hiura Y., Tachibana H., Arakawa R., Aoyama N., Okabe M., Sakai M., and Yamada K.
Specific accumulation of g and d-tocotrienols in tumor and their antitumor effect in vivo.
J. Nutr. Biochem., 20, 607-613. (2009)

Maruyama S, Akasaka T., Yamada K, and Tachibana H.
Protein-bound polysaccharide-K (PSK) directly enhanced IgM production in the human B cell line BALL-1.
Biomed. Pharmacother., 63 409-412 (2009)

Lee JH, Tachibana H, Morinaga Y, Fujimura Y., and Yamada K.
Modulation of proliferation and differentiation of C2C12 skeletal muscle cells by fatty acids.
Life Sci., 84, 415-420 (2009)

Tachibana H.
Molecular Basis for Cancer Chemoprevention by Green Tea Polyphenol EGCG.
Forum Nutr., 61, 156-169 (2009)

2008年

Umeda D, Yano S, Yamada K, and Tachibana H.
Green tea polyphenol epigallocatechin-3-gallate (EGCG) signaling pathway through 67-kDa laminin receptor
J. Biol. Chem., 283, 3050-3058 (2008)

Fujimura Y., Umeda D., Yamada K., and Tachibana H.
The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins
Arch. Biochem. Biophys., 476, 133-138 (2008)

Umeda D., Yamada K., and Tachibana H.
Identification of eukaryotic translation elongation factor 1A as a downstream mediator of EGCG signaling through 67-kDa laminin receptor
J. Clin. Biochem. Nutr., 43, 113-116 (2008)

Yano S., Fujimura Y., Umeda D., Miyase T., Yamada K., and Tachibana H.
Relationship between the biological activities of methylated derivatives of EGCG and their cell surface binding activities
J. Clin. Biochem. Nutr., 43, 473-476 (2008)

Fujimura Y., Umeda D., Yano S., Maeda-Yamamoto M., Yamada K., and Tachibana H.
The 67kDa laminin receptor mediates anti-allergic effects of (-)-epigallocatechin-3-O-(3-O-methyl) gallate
J. Clin. Biochem. Nutr., 43, 477-480 (2008)

Umeda D, Yano S, Yamada K, and Tachibana H.
Involvement of 67-kDa laminin receptor-mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells
Biochem. Biophys. Res. Commun., 371,172-176 (2008)

Maruyama, S., Yamada, K., and Tachibana, H.
Cistanche salsa extract induced apoptosis in the human Burkitt’s lymphoma cell lone Namalwa.
J. Trad. Med., 25, 24-27 (2008)

Tachibana, H.
Green Tea polyphenol EGCG signaling pathway though 67kDa laminin receptor.
J. Pharmacol. Sci., 106, Supl.I, 25p (2008)

Yamasaki, M., Tachibana, H., Yamada, A., Ochi, Y., Madhyastha, H., Nishiyama, N., and Yamada, K.
Oleic acid prevents apoptotic cell death induced by trans10, cis12 isomer of conjugated linoleic acid via p38 MAP kinase dependent pathway.
In Vitro Cell. Dev. Biol., 44, 290-294 (2008)

Umeda, D., Yamada, K., and Tachibana, H.
H89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) induces reduction of myosin regulatory light chain phosphorylation and inhibits cell proliferation.
Eur. J. Pharm., 590, 61-66 (2008)

立花宏文
緑茶カテキン受容体を介したカテキンの機能性発現とシグナリング
栄養学研究の最前線,　建帛社,　93-107 (2008)

山本(前田)万里、立花宏文、佐野満昭
「べにふうき」緑茶
化学と生物, 46 (3), 214-216 (2008)

山本(前田)万里、立花宏文、佐野満昭
メチル化カテキン含有「べにふうき」緑茶のアレルギー性鼻炎症状軽減効果
アレルギー・免疫, 15(5), 60-67 (2008)

立花宏文
緑茶カテキン受容体を介したカテキンの機能性発現機構
日本薬理学雑誌, 132, 145-149 (2008)

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2007年

Nakaya M, Onda H, Sasaki K, Yukiyoshi A, Tachibana H, and Yamada K.
Effect of royal jelly on bisphenol A-induced proliferation of human breast cancer cells.
Biosci. Biotechnol. Biochem., 71, 253-255 (2007)

Ikeda Y, Murakami A, Fujimura Y, Tachibana H, Yamada K, Masuda D, Hirano K, Yamashita S, and Ohigashi H.
Aggregated Ursolic Acid, a Natural Triterpenoid, Induces IL-1beta Release from Murine Peritoneal Macrophages: Role of CD36.
J. Immunol., 178, 4854-4664 (2007)

Yano S, Umeda D, Yamashita T, Ninomiya Y, Sumida M, Fujimura Y, Yamada K, and Tachibana H.
Dietary flavones suppresses IgE and Th2 cytokines in OVA-immunized BALB/c mice.
Eur. J. Nutr., 46, 257-263 (2007)

Yano S, Fujimura Y, Umeda D, Miyase T, Yamada K, and Tachibana H.
Relationship between the Biological Activities of Methylated Derivatives of (-)-Epigallocatechin-3-O-gallate (EGCG) and Their Cell Surface Binding Activities.
J. Agric. Food Chem., 55, 7144-7148 (2007)

Fujimura Y, Umeda D, Yano S, Maeda-Yamamoto M, Yamada K, and Tachibana H.
The 67kDa laminin receptor as a primary determinant of anti-allergic effects of O-methylated EGCG.
Biochem. Biophys. Res. Commun., 364, 79-85 (2007)

Miyamoto-Yamasaki Y, Yamasaki M, Tachibana H, and Yamada K.
Induction of endoreduplication by a JNK inhibitor SP600125 in human lung carcinoma A 549 cells.
Cell Biol. Int., 31, 1501-1506 (2007)

Maruyama, S., Yamada, K., and Tachibana, H.
Cistanche salsa extract enhanced IgM production in the human B cell line BALL-1.
J. Trad. Med., 24, 209-211 (2007)

柘植圭介, 渡部弥生, 前田徳秀, 阿部真一, 鶴橋亨, 吉村臣史, 吉木政弘, 立花宏文, 山田耕路.
スサビノリ水溶性低分子画分のHL-60細胞の増殖に及ぼす影響
日本食品科学工学会誌, 54, 241-246 (2007)

立花宏文、矢野和美、山田耕路
大豆成分の抗アレルギー性発現に関与する標的分子に関する研究
大豆たん白質研究, 10, 128-133（2007）

Umeda D., Yano S., Yamada K., and Tachibana H.
Green tea polyphenol EGCG signaling through the 67kDa laminin receptor
Proceeding of 2007 International conference on O-CHA (tea) culture and science, Health Benefits, in press

Tachibana H., Fujimura Y., Ninomiya Y., Hasegawa Y., Nkakayama K., and Yamada K.
Molecular basis for inhibition of IgE production by tea polyphenol strictinin.
Proceeding of 2007 International conference on O-CHA (tea) culture and science, Health Benefits, in press

Hasegawa Y., Fujimura Y., Yano S., Yamada K., and Tachibana H.
Downregulation of the high-affinity IgE receptor expression on mast cells by green tea catechin EGCG
Proceeding of 2007 International conference on O-CHA (tea) culture and science, Health Benefits, in press

Fujimura Y., Umeda D., Yamada K., and Tachibana H.
Structure-activity relationship of 67 kDa laminin receptor-mediated function of tea polyphenols
Proceeding of 2007 International conference on O-CHA (tea) culture and science, Health Benefits, in press

Ogawa N., Fujimura Y., Sumida M., Tsuruda S., Yamada K., and Tachibana H.
Identification of EGCG binding site in the green tea polyphenol receptor 67LR
Proceeding of 2007 International conference on O-CHA (tea) culture and science, Health Benefits, in press

Goto Y., Fujimura Y., Umeda D., Yamada K., and Tachibana H.
Green tea polyphenol EGCG-induced cell death pathway through the 67 kDa laminin receptor
Proceeding of 2007 International conference on O-CHA (tea) culture and science, Health Benefits, in press

Tachibana H., Umeda D., Fujimura Y., and Yamada K.
Green tea polyphenol EGCG signaling through 67kDa laminin receptor
J. Clin. Biochem. Nutr., 41, Suppl., 27 (2007)

Umeda D., Yamada K., and Tachibana H.
Identification of eukaryotic translation elongation factor 1A as a downstream mediator of EGCG signaling through 67-kDa laminin receptor
J. Clin. Biochem. Nutr., 41, Suppl., 62 (2007)

Ikeda Y., Murakami A., Fujimura Y., Tachibana H., Yamada K., Masuda D., Hirano K., Yamashita S., and Ohigashi H.
Aggregated ursolic acid, a natural triterpenoid, bind to CD36 for inducing interleukin-1b release from murine peritoneal macrophages
J. Clin. Biochem. Nutr., 41, Suppl., 99 (2007)

Yano S., Fujimura Y., Umeda D., Miyase T., Yamada K., and Tachibana H.
Relationship between the biological activities of methylated derivatives of EGCG and their cell surface binding activities
J. Clin. Biochem. Nutr., 41, Suppl., 145 (2007)

Fujimura Y., Umeda D., Yano S., Maeda-Yamamoto M., Yamada K., and Tachibana H.
The 67kDa laminin receptor mediates anti-allergic effects of (-)-epigallocatechin-3-O-(3-O-methyl) gallate
J. Clin. Biochem. Nutr., 41, Suppl., 145 (2007)

Tachibana H., Fujimura Y., Ogawa N., Sumida M., Tsuruda S., and Yamada K.
Identification of EGCG binding site in the green tea polyphenol receptor 67LR
J. Clin. Biochem. Nutr., 41, Suppl., 145 (2007)

Hiura Y., Arakawa R., Sakai M., Okabe M., Tachibana H., and Yamada K.
Effect of tocotrienols on the growth of mouse hepatoma MH134 cells in vitro and in vivo
J. Clin. Biochem. Nutr., 41, Suppl., 149 (2007)

Yamada K., Lee JH., Seo KIL., and Tachibana H.
Development of multi-functional foods
Rep. Jap. Assoc. Biol. Func. Res., 11, 1-11 (2007)

Tachibana H.
Anti-allergic natural products
Research Focus on Natural products and the Body's Immune and Inflammatory Systems , Suk, K. ed. 169-187 (2007)

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2006年

Nakaya, M., Tachibana, H., and Yamada, K.
Effect of estrogens on interferon-γ producing cell population of mouse splenocytes
Biosci. Biotechnol. Biochem., 70, 47-53 (2006)

Yamasaki M, Kitagawa T, Koyanagi N, Chujo H, Maeda H, Kohno-Murase J, Imamura J, Tachibana H, and Yamada K.
Dietary effect of pomegranate seed oil on immune function and lipid metabolism in mice.
Nutrition., 22, 54-59 (2006)

Sakai, M., Okabe, M., Yamasaki, M., Tachibana, H., and Yamada, K.
Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells.
J Nutr Biochem. (2006)

Yano, S., Umeda, D., Maeda, N., Fujimura, Y., Yamada, K., and Tachibana, H.
Dietary apigenin suppresses IgE and inflammatory cytokines production in C57BL/6N mice.
J. Agric. Food Chem, 54, 5203-5207 (2006)

Fujimura,Y., Umeda, D., Kiyohara, Y., Sunada, Y., Yamada, K., and Tachibana, H.
The involvement of the 67 kDa laminin receptor-mediated modulation of cytoskeleton in the degranulation inhibition induced by epigallocatechin-3-O-gallate
Biochem. Biophys. Res. Commun., 348, 524-531 (2006)

Maeda, N., Yoshimi, K., Tachibana, H., and Yamada, K.
Soy-derived immunoglobulin production stimulating factor enhances IgM production of mouse spleen lymphocytes
J. Food Sci., 71, 643-647 (2006)

Kobayashi, S., Ogawa, N., Fujimura, Y., Tachibana, H., and Yamada, K.
Water-soluble component in dried chrysanthemum flower stimulates tumor necrosis factor-production by mouse macrophage-like cell line RAW264.7.
Food Sci. Technol. Res., 12(2), (2006)

立花宏文、矢野和美、山田耕路
大豆サポニンの高親和性IgE受容体発現抑制効果
大豆たん白質研究、 in press（2006）

児林聡美、小川直人、藤村由紀、立花宏文、山田耕路
不知火姫菊抽出液のTNF-α産生促進効果
日本食品科学工学会誌、53, 430-436 (2006)

立花宏文
免疫の種類と働き
免疫と栄養
幸書房, 37-55 (2006)

立花宏文
免疫機能と栄養
アクティブシニア社会の食品開発指針,
サイエンスフォーラム, 152-159（2006）

藤村由紀、山本（前田）万里、立花宏文
抗アレルギー作用, 茶の効能と応用開発
シーエムシー出版, 55-63 (2006)

立花宏文
茶カテキン
食品機能性の科学
産業技術サービスセンター　印刷中（2007）

佐々木恭子、冨永堅志、立花宏文、山田耕路
ウナギ油の体調調節機能
生物機能研究会誌, 6, 34-39 (2006)

立花宏文
緑茶カテキン受容体の発見
化学と生物,44 (7), 432-434 (2006)

立花宏文
食品科学の新しい視点
学術月報, 59 (5), 346-347 (2006)

山本(前田)万里、佐野満昭、宮瀬敏男、立花宏文、永井寛、鈴木優子
メチル化カテキンを含む茶葉「べにふうき」を原料とした緑茶を容器詰め飲料と して製品化
農林水産技術研究ジャーナル, (2006)

山本(前田)万里、立花宏文
茶葉の抗アレルギー作用
月刊バイオインダストリー、(2006)

梅田大介、立花宏文
緑茶カテキン受容体を介したカテキンの抗がん、抗アレルギー作用
農林水産技術研究ジャーナル, 29 (7), 24-28 (2006)

立花宏文
植物ポリフェノールの抗アレルギー作用
Food style 21, 10 (7) 44-46 (2006)

立花宏文
緑茶カテキン受容体を介したカテキンの機能性発現
バイオサイエンスとインダストリー, 64(12), 680-682 (2006)

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2005年

S. Yano, H. Tachibana and K. Yamada
Flavones suppress the expression of the high-affinity IgE receptor FcepsilonRI in human basophilic KU812 cells
J Agric Food Chem., 53, 1812-1817, 2005.

Nakaya, M., Yamasaki, M., Tachibana, H., and Yamada, K.
IgM production of lymphocytes from C57BL/6N mice was stimulated by estrogen treated splenic adherent cells.
Immunol. Lett., 98, 225-231, 2005.

Umeda, D., Tachibana, H, and Yamada, K.
Epigallocatechin-3-O-gallate disrupts stress fibers and the contractile ring by reducing myosin regulatory light chain phosphorylation mediated through the target molecule 67kDa laminin receptor.
Biochem. Biophys. Res. Commun., 333, 628-635, 2005.

Yamasaki, M, Miyamoto, Y, Chujo, H, Nishiyama, K, Tachibana,H, Yamada, K
Trans10,cis12-conjugatedlinoleicacidinducesmitochondria-related apoptosisandlysosomal destabilizationinrat hepatomacells
Biochim Biophys Acta. 1735, 176-184, 2005.

Fujimura,Y., Yamada, K., and Tachibana, H.
A lipid raft-associated 67 kDa laminin receptor mediates suppressive effect of epigallocatechin-3-O-gallate on FceRI expression
Biochem. Biophys. Res. Commun., 336, 674-681 (2005)

立花宏文
嗜好食品,食品学
建白社, 189-206 (2005)

立花宏文
抗アレルギー食品開発のターゲット,抗アレルギー食品開発ハンドブック
サイエンスフォーラム, 67-82 (2005)

立花宏文
緑茶カテキンエピガロカテキンガレート,ガン予防食品開発の新展開
シーエムシー出版, 227-237 (2005)

Nakaya, M., Tachibana, H., and Yamada, K.
Isoflavone genestein and daizein up-regulate LPS-inducible oxide synthase activity through estrogen receptor pathway in RAW264.7 cells
Biochem. Pharmacol., 71, 108-114 (2005)

Yasuda, S., Wu, P.-O., Okabe, M., Tachibana, H. and Yamada K.
Tissue-specific distribution of genistein, daizein and bisphenol A in male Sprague-Dawley rats after intragastric administration
Food Sci. & Tech. Res., 11, 187-193 (2005)

Yamasaki, M., Nishida, E., Nou, S., Tachibana, H., and Yamada, K.
Cytotoxity of the trans10, cis12 isomer of conjugated linoleic acid on rat hepatoma and its modulation by other fatty acids, tocopherol, and tocotrienol
In Vitro Cell. Dev. Biol. Anim., 41, 239-244 (2005)

Umeda, D., Tachibana, H., and Yamada, K.
Epigallocatechin-3-O-gallate suppresses myosin II regulatory light chain phosphorylation
Proceedings of 2004 international conference O-CHA (tea) culture and science, 613-614 (2005)

Yano, S., Tachibana, H., Miyase, T., Maeda-Yamamoto, M., Sano, M., Fujimura, Y. and Yamada, K.
The suppressive effect of methylated catechins on FceRI expression and their cell surface binding activities
Proceedings of 2004 international conference O-CHA (tea) culture and science, 555-556 (2005)

Tachibana, H., Koga, K., Fujimura Y., and Yamada, K.
A receptor for epigallocatechin-3-O-gallate:67 kDa laminin receptor mediates anticancer action of EGCG
Proceedings of 2004 international conference O-CHA (tea) culture and science, 473-474 (2005)

Fujimura, Y., Yamada, K., and Tachibana, H.
67 kDa laminin receptor mediates an anti-allergic effect of epigallocatechin-3-O-gallate.
Proceedings of 2004 international conference O-CHA (tea) culture and science, 549-550 (2005)

Sumida, M., Tachibana, H., Fujimura, Y., and Yamada, K.
67 kDa laminin receptor sensitizes human hepatocytes to tea polyphenol (-)-epigallocatechin-3-O-gallate.
Proceedings of 2004 international conference O-CHA (tea) culture and science, 477-478 (2005)

Tahara, C., Tachibana, H., Fujimura, Y., and Koji Yamada, K.
67 kDa laminin receptor sensitizes human lung cancer to epigallocatechin-3-O-gallate.
Proceedings of 2004 international conference O-CHA (tea) culture and science, 475-476 (2005)

Sano, M., Yoshida, R., Sakurai, K., Miyase, T., Tachibana, H., and Maeda-Yamamoto, M.
Antioxidant activites of O-methylated catechins and the C-2 epimers.
Proceedings of 2004 international conference O-CHA (tea) culture and science, 524-525 (2005)

佐々木恭子、冨永堅志、立花宏文、山田耕路
ウナギ油の体調調節機能
生物機能研究会誌, 6, 34-39 (2006)

Nakaya M., Tachibana H., and Yamada K.
Immunoregulatory functions of estrogenic compounds; antibody, cytokine and nitric oxide production
Proceedings of International Joint Symposium between Japan and Korea,The Recent Status and Perspectives of Agricultural Environmental and Biotechnology 2005, 28-36 (2005)

2004年

Y. Fujimura, H. Tachibana and K. Yamada.
Lipid raft-associated catechin suppresses the FcεRI expression by phosphorylation of the extracellular signal-regulated kinase 1/2.
FEBS Lett. 556, 204-210, 2004.

S. Yasuda, P-S. Wu, E. Hattori, H. Tachibana and K. Yamada.
Simultaneous determination of isoflavones and bisphenol A in rat serum by high performance liquid chromatography coupled with coulometric array detection.
Biosci. Biotechnol. Biochem. 68, 51-58, 2004.

H. Tachibana, K. Koga, Y. Fujimura and K. Yamada
A receptor for green tea polyphenol EGCG.
Nature structural & molecular biology. 11,1-2, 2004.

内藤聖子, 劉忠峰, 黒岩中, 音成道彦, 田中守, 清永明, 田中宏暁, 立花宏文, 山田耕路, 新藤宗洋
成人男性における白血球数および好中球貪食能の日内変動について.
九大農学芸誌, 59 (1), 9-13, 2004

A. Hirao, M. Yamasaki, H. Chujo, N. Koyanagi, H. Kanouchi, S. Yasuda, A. Matsuo, E. Nishida, T. Rikimaru, E. Tsujita, M. Shimada, Y. Maehara, H. Tachibana and K. Yamada
Effect of dietary conjugated linoleic acid on liver regeneration after a partial hepatectomy in rats.
J. Nutr. Sci. Vitaminol, 50, 9-12, 2004.

山崎正夫, 山田耕路
共役リノール酸のはたらき.
山田耕路編「食品成分のはたらき」, 朝倉書店, pp. 91-104, 2004.

K. Yamada
Creation of multi-functional foods.
Proceedings on "Neutraceuticals and Medicinal Food", pp. 26-39, 2004.

山田耕路
九州大学農学部および生物資源環境科学府の教育システムについて
大学教育, 10, 107-117, 2004.

岡部正明, 安田伸, 荒巻文香, 佐々木恭子, 中谷真子, 服部絵美, 立花宏文, 山田耕路
大豆中の機能性因子の利用効率に及ぼす大豆粉末粒径の影響.
日食化誌, 11(1), 26-31, 2004.

立花宏文, 山田耕路
茶葉成分ストリクチニンのIgE産生抑制機構
食品工業, 47 (12), 27-35, 2004.

荒巻文香, 児林聡美, 大石文菜, 立花宏文, 山田耕路
マウス脾臓リンパ球における抗体およびサイトカイン産生に及ぼす菊抽出液の影響.
食科工誌, 51 (6), 304-308, 2004.

岡部正明, 坂井緑, 前田徳秀, 宮本有美, 立花宏文, 山田耕路.
Sprague-Dawleyラットの免疫機能および脂質代謝に及ぼすアマニ種子摂食の影響.
食科工誌, 51 (7), 352-357, 2004.

M. Yamasaki, T. Kitagawa, H. Chujo, N. Koyanagi, E. Nishida, M. Nakaya, K. Yoshimi, H. Maeda, S. Nou, T. Iwata, K. Ogita, H. Tachibana and K. Yamada.
Physiological difference between free and triglyceride-type conjugated linoleic acid on the immune function of C57BL/6N mice.
J. Agric. Food Chem., 52 (11), 3644-3648, 2004.

K. Tsuge, M. Okabe, T. Yoshimura, T. Sumi, H. Tachibana and K. Yamada
Dietary effects of porphyran from Porphyra yezoensis on growth and lipid metabolism of Sprague-Dawley rats.
Food Sci. Technol. Res., 10 (2), 147-151, 2004.

山田耕路
細胞実験と動物実験の組合せによる食品機能の検定
食科工誌, 51 (8), 377-381, 2004.

M. Sakai, M. Okabe, M. Yamasaki, H. Tachibana and K. Yamada
Induction of apoptosis by tocotrienol in rat hepatoma dRLh-84 cells.
Anticancer Res., 24, 1683-1688, 2004

S. Yasuda, M. Tada, K. Yamada and K. Takahata
Supressive effects of ascorbate derivatives on ultraviolet- B-induced injury in HACAT human keratinocytes.
In Vitro Cell. Develop. Biol. Animal, 40, 71-73, 2004.

立花宏文
茶成分の免疫調節作用.
食品成分のはたらき, 朝倉書店　121-140, 2004

立花宏文
ストリクチニンとは？.
今話題のべにふうき緑茶を知りたい （社）静岡県茶業会議所編pp6-7, 2004

立花宏文
緑茶の渋みは健康増進シグナル？
九大広報第35号pp12-13, 2004

立花宏文
茶とがん抑制作用
月刊「茶」, 57, 2-3, 2004

Fujimura, Y., Tachibana, H., Kumai, R., and Yamada, K.
A difference between epigallocatechin-3-gallate and epicatechin-3-gallate on anti-allergic effect is dependent on their distinct distribution to lipid rafts
Biofactors, 21, 133-135,2004.

Tachibana, H., Fujimura, Y., and Yamada, K.
Tea polyphenol epigallocatechin-3-gallate associates with plasma membrane lipid rafts: Lipid rafts mediate anti-allergic action of the catechin.
Biofactors, 21, 383-385, 2004.

Umeda, D., Tachibana, H., and Yamada, K.
Tea catechin, epigallocatechin-3-O-gallate suppresses myosin II regulatory light chain phosphorylation.
Biofactors, 21, 387-389, 2004.

Maeda-Yamamoto, M., Inagaki, N., Kitaura, J., Chikumoto, T., Kawahara, H., Kawakami,Y., Sano, M., Miyase, T., Tachibana, H., Nagai, H., and Kawakami, T.
O-methylated catechins from tea leaves inhibit multiple protein kinases in mast cells
J. Immunol., 172, 4486-4492, 2004

中谷真子，立花宏文，山田耕路
植物由来エストロゲン様物質による細胞間相互作用を介した免疫調節機構
生物機能研究会誌，8，1-4，2004．

岡部正明，立花宏文，山田耕路
トコトリエノールの体調調節機構に関する研究
生物機能研究会誌，8，16-19，2004．

中條瞳，立花宏文，山田耕路
共役リノール酸の制癌効果
生物機能研究会誌，8，20-23，2004．

B. O. Lim, K. Yamada and B. P. Yu
Relationship of biological aging and dietary restriction.
Rep. Jap. Assoc. Biol. Func. Res, 8, 24-33, 2004.

山田耕路
食品の安全性の地域認証システムと地場産業活性化に関する提言
生物機能研究会誌，8，38-41，2004

吉村臣史，柘植圭介，服部新，小金丸和義，墨利久，阿部真一，西野志津男，寛松正剛，宮本有美，山田耕路
未利用食品資源の有効利用に関する研究. ノリ由来ポルフィランオリゴ糖の免疫賦活能及びサイトカイン産生能について
佐賀県工業技術センター研究報告書，2003-12，63-67，2004

山田耕路
書評「機能性食品便覧 特定保健用食品からサプリメント・健康食品まで」
栄食誌，57 (6)，291，2004

山田耕路
アレルギーと脂質
佐藤清隆・柳田晃良・和田俊編「機能性脂質のフロンティア」，シーエムシー，pp.27-32，2004

B. O. Lim, K. Yamada, B-G. Cho, T. Jeon, S-G, Hwang, T. Park, S. A. Kang and D. K. Park.
Comparative study on the modulation of IgE and cytokine production by Phellinus linteus grown on germinated brown Rice, Phellinus Linteus and germinated brown rice in murine splenocytes.
Biosci Biotechnol Biochem. 68(11), 2391-2394, 2004

立花宏文、岡達三
緑茶カテキンはラミニンレセプター (67LR)を介してガン細胞の増殖を抑制する
ビタミン, 78 (10), 513-514, 2004

2003年

M. Yamasaki, A. Ikeda, M. Oji, Y. Tanaka, A. Hirao, M. Kasai, T. Iwata, H. Tachibana and K. Yamada.
Modulation of body fat and serum leptin levels by dietary conjugated linoleic acid in Sprague-Dawley rats fed various fat-level diets.
Nutrition, 19, 30-35, 2003.

立花宏文, 山本（前田）万里, 山田耕路.
茶葉から新たに見つかった抗アレルギー物質ストリクチニン.
農業および園芸, 78 (1), 7-11, 2003.

岡本威明, 吉見一真, 立花宏文, 山田耕路.
マウス脾臓リンパ球の抗体産生に及ぼす食品タンパク質およびペプチドの影響.
食科工誌, 50 (2), 72-77, 2003.

山崎正夫, 山田耕路.
共役脂肪酸の免疫調節機能,
食品工業, 46 (6), 31-35, 2003.

K. Yamada, Y. Tokunaga, A. Ikeda, K. Ohkura, S. Kaku-Ohkura, S. Mamiya, B.O. Lim and H. Tachibana.
Effect of dietary fiber on the lipid metabolism and immune function of aged Sprague-Dawley rats.
Biosci. Biotechnol. Biochem. 67 (2), 429-433, 2003.

M. Yamasaki, H. Chujo, A. Hirao, N. Koyanagi, T. Okamoto, N. Tojo, A. Oishi, T. Iwata, Y. Yamauchi-Sato, T. Yamamoto, K. Tsutsumi, H. Tachibana and K. Yamada.
Immunoglobulin and cytokine production from spleen lymphocytes is modulated in C57BL/6J mice by dietry cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid.
J. Nutr., 133, 784-788, 2003.

岡部正明, 松尾綾, 西田江里, 立花宏文, 山田耕路.
Sprague-Dawleyラットの脂質代謝および免疫機能に及ぼす活性生菌製剤の摂食効果.
食科工誌, 50 (5), 224-229, 2003.

山田耕路.
食物アレルギーと食糧.
第12回日本アレルギー学会春季臨床大会講演記録集, 114-123, 2003.

山田耕路.
農学研究院・言語文化研究院合同FDを実施して.
大学教育, 9, 123-128, 2003.

P-S. Wu, S. Yasuda, H. Tachibana and K. Yamada.
Voltage dependency in coulometric analysis of tea polyphenols and isoflavones in foodstuffs.
Food Sci. Technol. Res., 9 (2), 180-184, 2003.

M. Yamasaki, H. Chujo, S. Nou, H. Tachibana and K. Yamada.
Alleviation of the cytotoxic activity induced by trans10, cis12-conjugated linoleic acid in rat hepatoma dRLH-84 cells by oleic or palmitoleic acid.
Cancer Lett., 196, 187-196, 2003.

B.O Lim, Z. Liu, H. Tachibana and K. Yamada.
Regulation of IgA production by foodstuffs.
Rep. Japn. Assoc. Biol. Func. Res., 7, 1-5, 2003.

宮崎義之, 音成道彦, 立花宏文, 山田耕路.
ペルオキシソーム増殖活性化受容体の生理機能.
生物機能研究会誌 7, 10-15, 2003.

岡本威明, 内藤聖子, 立花宏文, 山田耕路.
NK細胞活性調節機構.
生物機能研究会誌 7, 21-25, 2003.

山田耕路.
すこやか食品の創製について.
生物機能研究会誌 7, 28-31, 2003.

荒巻文香, 大石文菜, 音成道彦, 内藤聖子, 劉忠峰, 立花宏文, 山田耕路.
各種癌細胞株の増殖に及ぼす菊花弁抽出液の影響.
食科工誌, 50 (10),493-497, 2003.

T. Utsunomiya, M. Shimada, T. Rikimaru, H. Hasegawa, Y. Yamashita, T. Hamatsu, M. Yamasaki, S. Kaku, K. Yamada and K. Sugimachi.
Antioxidant and anti-inflammatory effects of a diet supplemented with sesamin on hepatic ischemia-reperfusion injury in rats.
Hepato-Gastroenterology, 50, 1609-1613, 2003.

叶内宏明, 中條瞳, 岡部正明, 松尾綾, 立花宏文, 山田耕路.
Sprague-Dawleyラットの抗体産生に及ぼす酢酸摂取の影響.
九大農学芸誌, 58 (1,2), 13-18, 2003.

音成道彦, 松原建史, 内藤聖子, 劉忠峰, 大瀬雄也, 庄野菜穂子, 田中守, 清永明, 田中宏暁, 新藤宗洋, 山田耕路.
血中乳酸閾値（LT）強度での自転車トレーニングがエネルギー基質としての脂質利用に及ぼす影響.
九大農学芸誌, 58 (1,2), 19-26, 2003.

Z. Liu, M. Otonari, S. Naito, S. Yasuda, H. Tanaka, H. Yoshioka, M. Oyabu, T. Tobina, R. Kanda, H. Tanaka, M. Shindo, H. Tachibana and K. Yamada.
Diurnal variation in secretory immunoglobulin A concentration.
J. Fac. Agr., Kyushu Univ. 48 (1, 2), 167-174, 2003.

柘植圭介, 吉村臣史, 小金丸和義, 墨利久, 岡部正明, 宮本有美, 山田耕路.
食品加工残渣の高度利用に関する研究. ラット腸管免疫系及び脂質代謝に対するスサビノリ由来ポルフィランの効果.
佐賀県工業技術センター研究報告. 2002-11, 67-71, 2003.

立花宏文, 藤村由紀, 矢野知美, 山田耕路.
大豆サポニンの免疫調節機能.
大豆たん白質研究, 6, 104-107, 2003.

I. Ikeda, K. Mitsui, R. Matsuoka, T. Hamada, S. Imabayashi, A. Uchino, K. Yamada and K. Imaizumi.
Cholesterol esterase bound to intestinal brush border membranes does not accelerate incorporation of micellar cholesterol into absorptive cells.
Biosci. Biotechnol. Biochem., 67 (11), 2381-2387, 2003.

山本（前田）万里，佐野満昭， 立花宏文
緑茶の抗アレルギー・がん転移抑制作用
化学と生物，41，442-447，2003.

2002年

山田耕路.
久木野憲司, 山本茂監修「栄養学英和辞典」,
金原出版, 2002.

山崎正夫, 山田耕路.
共役リノール酸の免疫調節機能,
食科工誌, 42 (2), 130-134, 2002.

Maeda-Yamamoto, M., Sano, M., Miyase, T., Tachibana, H., Isemura, M., Hakamata, K., Kawakami, Y., and Kawakami, T.
EGCG derivatives of tea inhibit protein kinase activities in mast cells and matrix metalloproteinase activities in highly metastatic cells.
Proceedings of 2001 International Conference on O-cha (Tea) Culture and Science. Session III, 188-191, 2002.

Sano, M., Suzuki, M., Miyase, T., Nakamura, Y., Yoshino, Y., Tachibana, H., and Maeda-Yamamoto, M.
Inhibitory effects of O-methylated catechin derivatives on mouse type-I allegy.
Proceedings of 2001 International Conference on O-cha (Tea) Culture and Science. Session III, 188-191, 2002.

Y. Kiyohara, H. Tachibana and K. Yamada.
Degranulation inhibition of human basophilic KU812 cells by green tea catechins and their cell surface binding.
Proceedings of 2001 International Conference on O-cha (Tea) Culture and Science. Session III, 188-191, 2002.

Y. Fujimura, H. Tachibana and K. Yamada.
Suppressive effect of catechin derivatives on the expression of the high affinity IgE recptor FceRI in human basophilic KU812 cells.
Proceedings of 2001 International Conference on O-cha (Tea) Culture and Science. Session III, 192-195, 2002.

H. Tachibana, T. Kubo, T. Miyase, S. Tanino, M. Yoshimoto,K. Nakao, K. Nakayama, M. Sano, M. Maeda-Yamamoto and K. Yamada.
Strictinin inhibits interkeukin 4-induced STAT6 activation and antigen-specific IgE production.
Proceedings of 2001 International Conference on O-cha (Tea) Culture and Science. Session III, 234-237, 2002.

立花宏文, 藤村由紀, 山田耕路.
緑茶ポリフェノールの抗アレルギー作用−ヒト好塩基球における高親和性IgE受容体発現の抑制.
食品工業, 45 (6), 25-30, 2002.

山本（前田）万里、佐野満昭、立花宏文、木幡勝則
新たにわかってきた緑茶の機能性　抗アレルギー作用、がん転移阻害作用
食品工業, 45, 18-24, 2002.

山田耕路.
食品成分の免疫調節機構に関する研究,
平成12・13年度科学研究費補助金（基盤研究B）研究成果報告書, 2000年3月.

立花宏文
IgE産生阻害作用
茶の機能-生体機能の新たな可能性 学会出版センター、250-255, 2002.

立花宏文
ヒト培養細胞を用いた食品成分の機能性評価
DOJIN NEWS 102, 1-4, 2002.

立花宏文
茶葉中の抗アレルギー成分の機能解析
日本食糧新聞3月4日, 2002.

B. O. Lim, R. W. Choue, D. K. Park, H. C. Kim, S. Y. Kim, K. Yamada and M. Sugano.
Effect of dietary level of pectin on immunoglobulin and cytokine production by mesenteric lymph node lymphocytes and interleukin-2 receptor in rats.
Food Sci. Technol. Res., 8 (1), 14-16, 2002.

K. Yamada, M. Okabe, K. Ohkura, M. Oji, M. Nonaka, I. Ikeda and H. Tachibana.
Dietary effect of a-tocopherol and tocotrienols on lipid metabolism and immune function of aged Sprague-Dawley rats.
Food Sci. Technol. Res., 8 (1), 59-63, 2002.

A. Akahoshi, Y. Goto, K. Murao, T. Miyazaki, M. Yamasaki, M. Nonaka, K. Yamada and M. Sugano.
Conjugated linoleic acid reduces body fats and cytokine levels of mice,
Biosci. Biotechnol. Biochem., 66 (4), 916-920, 2002.

長田恭一, 山田耕路.
食事と酸化コレステロール.
オレオサイエンス, 2 (5), 249-256, 2002.

山田耕路.
学生参加型授業の試み,
大学教育, 8, 81-86, 2002.

山田耕路.
食品成分のアレルギー調節機能,
生物機能研究の進歩１, アイピーシー, pp. 1-78, 2002.

立花宏文
緑茶成分の生体調節機能
生物機能研究の進歩１, アイピーシー, pp. 79-116, 2002.

K. Koba, A. Akahoshi, M. Yamasaki, K. Tanaka, K. Yamada, T. Iwata, T. Kamegai, K. Tsutsumi and M. Sugano.
Dietary conjugated linolenic acid in relation to conjugated linoleic acid differently modifies body fat mass and serum and liver lipid levels in rats.
Lipids, 37 (4): 343-350, 2002.

立花宏文, 山田耕路.
茶成分の抗アレルギー作用について.
食品と科学. 44 (7), 73-76, 2002.

T. Okamoto, T. Sugahara, H. Tachibana and K. Yamada.
Enhancement of immunoglobulin productivity of human-human hybridoma HB4C5 cells by histone.
Biosci. Biotechnol. Biochem., 66 (6), 1241-1245, 2002.

I. Ikeda, R. Matsuoka, T. Hamada, K. Mitsui, S. Imabayashi, A. Uchino, M. Sato, E. Kuwano, T. Itamura, K. Yamada, K. Tanaka and K. Imaizumi.
Cholesterol esterase accelerates intestinal cholesterol absorption.
Biochim. Biophys. Acta, 1551, 34-44, 2002.

山田耕路, 呉博聖, 立花宏文.
食品中の機能性成分の相乗効果.
New Food Industry, 44 (8), 17-21, 2002.

Y. Miyazaki, H. Tachibana and K. Yamada.
Inhibitory effect of peroxisome proliferator-activated receptor-g ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39.
Biochem. Biophys. Res. Commun., 295, 547-552, 2002.

D-H. Han, M.S. Denison, H. Tachibana and K. Yamada.
Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids.
Biosci. Biotechnol. Biochem., 66 (7), 1479-1487, 2002.

M. Okabe, M. Oji, I. Ikeda, H. Tachibana and K. Yamada.
Tocotrienol levels of various tissues in Sprague-Dawley rats after intragastric administration of tocotrienol.
Biosci. Biotechnol. Biochem., 66 (8), 1768-1771, 2002.

M. Takasugi, M. Sugano and K. Yamada.
Measurement of total and food component-specific IgA in human saliva.
Food Sci. Technol. Res., 8 (3), 273-275, 2002.

D-H. Han, M.S. Denison, H. Tachibana and K. Yamada.
Effect of estrogenic compounds on immunoglobulin production by mouse splenocytes.
Biol. Pharm. Bull., 25 (10), 1263-1267, 2002.

B.O. Lim, K. Yamada and R.O. Choue.
The key role of cytokine in immunopethogenesis of inflammatory bowel diseases.
Rep. Jap. Asso. Biol. Func. Res., 6, 4-17, 2002.

宮崎義之, 立花宏文, 山田耕路.
多価不飽和脂肪酸および脂質酸化物の免疫調節機能とその作用機構.
生物機能研究会誌, 6, 18-24, 2002.

岡本威明, 菅原卓也, 立花宏文, 山田耕路.
食品タンパク質およびペプチドの免疫調節機構.
生物機能研究会誌, 6, 25-31, 2002.

藤村由紀, 山田耕路, 立花宏文.
ヒト好塩基球における高親和性IgE受容体発現の制御.
生物機能研究会誌, 6, 36-44, 2002.

山田耕路.
アメリカ東海岸のバイオベンチャー支援システムと九州地区におけるバイオ産業の支援について.
生物機能研究会誌, 6, 70-78, 2002.

Y. Fujimura, H. Tachibana and K. Yamada.
Peroxisome proliferator-activated receptor ligands negatively regulate the expression of the high-affinity IgE recptor FcεRI in human basophilic KU812 cells.
Biochem. Biophys. Res. Commun., 297, 193-201, 2002.

Y. Fujimura, H. Tachibana, M. Maeda-Yamamoto, T. Miyase, M. Sano and K. Yamada.
Antiallergic tea catechin, (-)-epigallocatechin-3-O-(3-O- methyl) gallate, suppresses FceRI expression in human basophilic KU812 cells.
J. Agric. Food Chem., 50 (20), 5729-5734, 2002.

安田伸, 宮崎義之, 服部絵美, 立花宏文, 山田耕路.
Sprague-Dawleyラットの脂質代謝、免疫機能に及ぼすイチョウ葉および竹エキス粉末の摂食効果.
九大農学芸誌, 57 (1), 17-25, 2002.

岡本威明, 吉見一真, 東條直己, 安田伸, 服部絵美, 立花宏文, 山田耕路.
Sprague-Dawley系ラットの脂質代謝および免疫機能に及ぼす大豆抽出物の摂食効果.
九大農学芸誌, 57 (1), 27-34, 2002.

P-S. Wu, Y. Tokunaga, K. Ohkura, A. Ikeda, M. Nonaka, H. Tachibana and K. Yamada.
Dietary effect of yeast extract or glutathione on lipid metabolism and immune function of Sprague-Dawley rats.
J. Fac. Agr., Kyushu Univ. 47 (1), 61-66, 2002.

Y. Fujimura, H. Tachibana and K. Yamada.
Downregulation of high affinity IgE receptor FcεRI expression in the human basophilic KU812 cells by a tea catechin.
Animal Cell Technology: Basic and Applied Aspects, Vol. 12, Ed. by S. Shirahata et al., Kluwer Academic, Netherlands, pp. 365-370, 2002.

Anti-allergic catechins of tea (Camellia sienesis).
Yamamoto-maeda, M., Kawamoto, K., Matsuda, N., Sano, M., Suzuki, N., Yoshimura, M., Tachibana, H., Kawakami, Y., and Kawakami, T.
Animal Cell Technology: Basic and Applied Aspects, Vol. 12, Ed. by S. Shirahata et al., Kluwer Academic, Netherlands, pp. 415-419, 2002.

M. Yamasaki, K. Mansho, Y. Ogino, M. Kasai, H. Tachibana and K. Yamada.
Regulation of serum leptin level by dietary conjugated linoleic acid in Sprague-Dawley rats.
Animal Cell Technology: Basic and Applied Aspects, Vol. 12, Ed. by S. Shirahata et al., Kluwer Academic, Netherlands, pp. 467-471, 2002.

高杉美佳子, 島田和子, 山田耕路.
大豆イソフラボンのアレルギー関連メディエーター放出抑制作用に関する研究.
大豆たん白質研究, 5, 99-102, 2002.

山田耕路, 韓達昊, 呉博聖, 安田伸, 菅野道廣, 立花宏文.
大豆イソフラボンおよび環境ホルモンの抗体産生調節作用.
大豆たん白質研究, 5, 103-107, 2002.

M. Yamasaki, H. Chujo, Y. Koga, A. Oishi, T. Rikimaru, M. Shimada, K. Sugimachi, H. Tachibana and K. Yamada.
Potent cytotoxic effect of trans-10, cis12 isomer of conjugated linoleic acid on rat hepatoma dRLh-84 cells.
Cancer Lett., 188, 171-180, 2002.

M. Yamasaki, A. Ikeda, A. Hirao, Y. Tanaka, T. Rikimaru, M. Shimada, K.
Sugimachi, H. Tachibana and K. Yamada.
Dose-dependent effect of dietary conjugated linoleic acid on the growth of rat hepatoma dRLh-84 cells in vivo.
J. Nutr. Sci. Vitaminol, 48 (6), 505-511, 2002.

2001年

大倉健一, 加来志保子, 大司麻利子, 立花宏文, 山田耕路.
Sprague-Dawleyラットの免疫機能に及ぼす玄麦玄米酢摂食の効果.
食科工誌, 48 (1), 14-19, 2001.

H. Tachibana, T. Kubo, T. Miyase, S. Tanino, M. Yoshimoto, M. Sano, M. Yamamoto-Maeda and K. Yamada.
Identification of an inhibitor for interleukin 4-induced ε germline transcription and antigen-specific IgE production in vivo.
Biochem. Biophys. Res. Commun., 280, 53-60, 2001.

M. Takasugi, Y. Tamura, H. Tachibana, M. Sugano and K. Yamada.
Development of assay system for immunoglobulin production regulatory factors using whole cell culture of mouse splenocytes.
Biosci. Biotechnol. Biochem., 65 (1), 143-149, 2001.

山本（前田）万里、佐野満昭、松田奈帆美、宮瀬敏男、川本恵子、鈴木直子、吉村昌恭、立花宏文、袴田勝弘
茶の品種、摘採期と製造法による抗アレルギー性カテキンEGCG3-Meの変動.
日本食品科学工学会誌, 48, 64-68, 2001.

山田耕路.
食品成分の機能と化学,
アイシーピー, 2001.

S. Kaku, S. Yunoki, K. Ohkura, M. Sugano, M. Nonaka, H. Tachibana and K. Yamada.
Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats.
Biosci. Biotechnol. Biochem., 65 (2), 315-321, 2001.

山田耕路.
食品中のアレルギー調節因子.
FOOD Style 21, 5 (3), 47-49, 2001.

山田耕路.
21Cの抗アレルギー食品のデザイン.
食品と開発, 36 (3), 12-14, 2001.

Y. Miyazaki, M. Yamasaki, H. Mishima, K. Mansho, H. Tachibana and K. Yamada.
Oxidative stress by visible light irradiation induces suppression of immunoglobulin production by mouse spleen lymphocytes.
Biosci. Biotechnol. Biochem., 65 (3), 593-598, 2001.

山田耕路.
講義内容の改訂における学生の授業評価の利用.
大学教育, 7, 81-90, 2001.

S. Okumura, T. Akao, H. Kanegae, N. Matsuo, M. Sugano and K. Yamada.
Adjuvant activity of synthetic cationic amphiphiles for production of IgG antibody in Sprague Dawley rats.
Food Sci. Techonol. Res., 7 (1), 67-71, 2001.

Y. Fujimura, H. Tachibana and K. Yamada.
A tea catechin suppresses the expression of the high-affinity IgE receptor FcεRI in human basophilic KU812 cells.
J. Agric. Food Chem., 49, 2527-2531, 2001.

山田耕路.
水溶性食物繊維の抗体産生調節機能.
日本食物繊維研究会誌, 5 (1), 1-9, 2001.

立花宏文, 山田耕路.
IgEの生成を調節する食品成分.
臨床免疫, 35 (5), 611-618, 2001.

立花宏文
第4回動物細胞工学シンポジウム「次世代医薬としてのモノクローナル抗体の臨床展開」を終えて
JAACT News Letter, 10, 78-80, 2001.

立花宏文
食品成分によるアレルギー予防をめざして
New Food Industry, (2001) 43, 7-12, 2001.

山田耕路.
九州大学硬式野球部長への就任にあたって.
防塁, 平成13年度前期号, 5-6, 2001.

Y. Miyazaki, Y. Tokunaga, K. Takagaki, S. Tsusaki, H. Tachibana and K. Yamada.
Effect of dietary cabbage fermentation extract and young barley leaf powder on immune function of Sprague-Dawley rats.
J. Nutr. Sci. Vitaminol., 47, 253-257, 2001.

D-H. Han, H. Tachibana and K. Yamada.
Inhibition of environmental estrogen-induced proliferation of human breast carcinoma MCF-7 cells by flavonoids.
In Vitro Cell. Develop. Biol. Animal, 37, 275-282, 2001.

加来志保子, 山田耕路, 菅野道廣.
ラットの脂質代謝および免疫機能に及ぼす食餌タンパク質と食餌脂肪の影響.
必須アミノ酸研究, 161, 99-103, 2001.

山田耕路.
熊本高校での野球の思い出.
江球会報, 第2号, 3, 2001.

叶内宏明, 岡部正明, 土井志真, 山田英生, 立花宏文, 山田耕路.
Sprague-Dawleyラットの抗体産生に及ぼすクロレラ粉末の摂食効果.
食科工誌, 48 (8), 634-636, 2001.

Y. Miyazaki, M. Noguchi, H. Tachibana and K. Yamada.
Polyunsaturated fatty acids are not essential for survival and proliferation of a human B cell line.
In Vitro Cell. Develop. Biol. Animal, 37, 399-401, 2001.

S. Kaku, K. Yamada and M. Sugano.
g-Linolenic acid modifies lipid and immune indices in rats: dose-dependency and dietary interaction. In "g-Linolenic Acid: Recent Advances in Biotechnology and Clinical Applications", ed. by Y-S. Huang and V. A. Ziboh,
AOCS Press, Champaign, Illinois, pp. 190-197, 2001.

呉博聖, 韓達昊, 安田伸, 山田耕路.
大豆イソフラボンの生体調節機能とその定量.
生物機能研究会誌, Vol. 5, 6-12, 2001.

山田耕路.
学会発表および講演の準備について.
生物機能研究会誌, Vol. 5, 21-24, 2001.

山田耕路, 韓達昊, 菅野道廣, 立花宏文.
大豆イソフラボンのエストロゲン活性発現抑制効果.
大豆たん白質研究, 4, 123-128, 2001.

H. Kanouchi, H. Tachibana, T. Oka and K. Yamada.
Recombinant expression of perchloric acid-soluble protein reduces cell proliferation.
Cell. Mol. Life Sci., 58, 1340-1343, 2001.

S. Kaku, K. Ohkura, S. Yunoki, M. Nonaka, H. Tachibana, M. Sugano and K. Yamada.
Dietary g-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats.
Prostagl. Leukotri. Essent. Fatty Acids, 65 (4), 205-210, 2001.

M. Sugano, A. Akahoshi, K. Koba, K. Tanaka, T. Okumura, H. Matsuyama, Y. Goto, K. Murao, M. Yamasaki, M. Nonaka and K. Yamada.
Dietary manipulations of body fat-reducing potential of conjugated linoleic acid in rats.
Biosci. Biotechnol. Biochem., 65 (11), 2535-2541, 2001.

山田耕路.
抗アレルギー素材の開発,
食品の包装, 33 (1), 25-32, 2001.

立花宏文.
食と健康「アレルギーの元を抑える茶成分」
中日新聞朝刊 7月8日, 2001.

M. Yamasaki, A. Ikeda, A. Hirao, Y. Tanaka, Y. Miyazaki, T. Rikimaru, M. Shimada, K. Sugimachi, H. Tachibana and K. Yamada.
Effect of dietary conjugated linoleic acid on the in vivo growth of rat hepatoma dRLh84.
Nutr. Cancer., 40 (2), 140-148, 2001.

2000年

K. Minehira, S. Inoue, M. Nonaka, K. Osada, K. Yamada and M. Sugano.
Effect of dietary protein type on oxidized cholesterol-induced alteration of lipid metabolism and indices of immune function in rats.
Biochim. Biophys. Acta, 1483, 141-153, 2000.

D-H. Han, Y. Miyazaki, H. Tachibana and K. Yamada.
Optimization of estrogenic activity detection method using human breast cancer MCF-7 cells.
J. Fac. Agr., Kyushu Univ., 44 (3-4), 339-348, 2000.

H. Tachibana, Y. Sunada, T. Miyase, M. Sano, M. Maeda-Yamamoto and K. Yamada.
Identification of a methylated tea catechin as an inhibitor of degranulation in human basophilic KU812 cells.
Biosci. Biotechnol. Biochem., 64 (2), 452-454, 2000.

H. Tachibana, H. Haruta, K. Ueda, T. Chiwata and K. Yamada.
Induction of light chain replacement in human plasma cells by caffeine is independent from both the upregulation of RAG protein expression and germ line transcription.
J. Biol. Chem., 25 (8), 5927-5933, 2000.

山田耕路.
食品成分の免疫調節機能.
生物機能研究会誌. 4 (1), 1-10, 2000.

立花宏文.
茶葉成分の新たな機能性を探る.
生物機能研究会誌. 4 (1), 25-29, 2000.

加来志保子, 柚木真一, 大倉健一, 大司麻利子, 野中美智子, 菅野道廣, 立花宏文, 山田耕路.
食品中の抗アレルギー成分の検索.
熊本県立大学環境共生学部紀要, 1, 17-25, 2000.

山田耕路.
食物繊維の抗体産生調節機能.
FFIジャーナル, 168, 26-32, 2000.

山田耕路.
食品バイオ研究の現場から.
バイオサイエンスとインダストリー, 58 (5), 347, 2000.

K. Osada, K. Minehira, S. Inoue, S. Nakamura, K. Yamada and M. Sugano.
Effect of oxidized cholesterol on age-associated changes to immune parameters in spleen lymphocytes and peritoneal exudate cells derived from rats.
Biosci. Biotechnol. Biochem. 64 (5), 1047-1051, 2000.

山田耕路監修.
大麦若葉「緑効末」健康法.
史輝出版, 2000.

N. Matsuo, K. Yamada, M. Mori, K. Shoji, T. Ueyama, S. Yunoki, K. Yamashita, M. Ozeki and M. Sugano.
Inhibition by dietary tea polyphenols of chemical mediator release from rat peritoneal exudate cells.
Biosci. Biotechnol. Biochem.,64 (7), 1437-1443, 2000.

山田耕路.
食品成分の動物細胞増殖制御機能について.
農化誌, 74 (9), 990-993, 2000.

M. Sugano, T. Koga and K. Yamada.
Lipids and immunology.
Asia Pacific J. Clin. Nutr., 9 (2), 146-152, 2000.

H. Kanouchi, T. Oka, K. Asagi, H. Tachibana and K. Yamada.
Expression and cellular distribution of perchloric acid-soluble protein is dependent on the cell proliferating states in NRK-52E cells.
Cell. Mol. Life Sci., 57, 1103-1108, 2000.

叶内宏明, 岡達三, 山田耕路.
過塩素酸可溶性タンパク質.
生物機能研究会誌, 4 (2), 57-60, 2000.

山田耕路.
科学論文のまとめ方.
生物機能研究会誌, 4 (2), 83-88, 2000.

山田耕路.
動物細胞工学ハンドブック,
朝倉書店, pp.19-26, 2000.

山田耕路, 韓達昊, 宮崎義之, 菅野道廣, 立花宏文.
ヒト乳癌MCF-7細胞の増殖に及ぼすイソフラボンの作用.
大豆たん白質研究, 3, 54-58, 2000.

M. Yamasaki, K. Mansho, Y. Ogino, M. Kasai H. Tachibana and K. Yamada.
Acute reduction of serum leptin level by dietary conjugated linoleic acid in Sprague-Dawley rats.
J. Nutr. Biochem., 11 (9), 467-471, 2000.

M. Yamasaki, K. Kishihara, K. Mansho, Y. Ogino, M. Kasai, M. Sugano, H. Tachibana and K. Yamada.
Dietary conjugated linoleic acid increases immunoglobulin productivity of Sprague-Dawley rat spleen lymphocytes.
Biosci. Biotechnol. Biochem., 64 (10), 2159-2164, 2000.

Y. Fujimura, H. Tachibana, N. Eto and K. Yamada.
Antigen binding of an ovomucoid specific antibody is affected by a carbohydrate chain located on the light chain variable region.
Biosci. Biotechnol. Biochem., 64 (11), 2298-2305, 2000.

山田耕路.
食物アレルギーと食品成分.
アレルギー, 49 (11), 1060-1062, 2000.

M. Yamasaki, K. Mansho, H. Mishima, G. Kimura, M. Sasaki, M. Kasai, H. Tachibana and K. Yamada.
Effect of dietary conjugated linoleic acid on lipid peroxidation and histological change in rat liver tissues.
J. Agric. Food Chem. 48 (12), 6367-6371, 2000.

P. Hung, J-Y. Gu, S. Kaku, S. Yunoki, K. Ohkura, I. Ikeda, H. Tachibana, M. Sugano, K. Yazawa and K. Yamada.
Dietary effect of eicosapentaenoic and docosahexaenoic acid esters on lipid metabolism and immune parameters in Sprague-Dawley rats.
Biosci. Biotechnol. Biochem., 64 (12), 2588-2593, 2000.

K. Yamada and H. Tachibana.
Recent topics in anti-oxidative factors.
BioFactors, 13, 167-172, 2000.

立花宏文
抗体の機能制御による生体機能修復をめざして -生物機能の新展開-人類の生存をかけて-
日本学術会議 50周年記念シンポジウム, 103-111, 2000.

佐野満昭、宮瀬敏男、立花宏文、山本万里
茶成分の抗アレルギー作用
Fragrance J. 4, 46-52, 2000.

佐野満昭、宮瀬敏男、立花宏文、山本万里
茶カテキン類の抗アレルギー作用について
Food Style, IV, 72-74, 2000.

T. Utsunomiya, M. Shimada, T. Rikimaru, K. Sugimachi, K. Ohkura, S. Kaku, K. Yamada, K. Taguchi.
Letter to the Editor. Correspondence re: M. Kondo et al.Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma (Clin. Cancer Res., 5, 4005-4012, 1999).
Clin. Cancer Res., 6 (12), 4965-4966, 2000.

T. Hara, H. Tachibana and K. Yamada.
Increase in histamine content and enhancement of high affinity IgE receptor FcεRI expression in the human leukemia KU812 cells upon treatment of hydrocortisone.
Cytotechnology, 34, 213-223, 2000.

Fujimura, Y., Tachibana, H., Eto, M., and Yamada, K.
Antigen binding of an ovomucoid specific monoclonal antibody is modulated by the carbohydrate chain on the light chain variable region.
Biosci. Biotech. Biochem, 64 (11), 2298-2305, 2000.

Tachibana, H., Chiwata, T., Nagahiro, Y., Haruta, H., and Yamada, K.
Induction of secondary light chain gene recombination in human plasma cells by caffeine is independent from both the up-regulation of RAG proteins expression and germ-line transcription .
In Vitro Cell. Dev. Biol., 36, 81A, 2000.

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