論文発表

• Ishibashi A, Udono M, Sato M, Katakura Y. Molecular Mechanisms for the Carnosine-Induced Activation of Muscle-Brain Interaction. Nutrients. 2023 Mar 19;15(6):1479. doi: 10.3390/nu15061479. PMID: 36986209; PMCID: PMC10057344.
• Fujiki T, Shinozaki R, Udono M, Katakura Y. Identification and Functional Evaluation of Polyphenols That Induce Regulatory T Cells. Nutrients. 2022 Jul 13;14(14):2862. doi: 10.3390/nu14142862. PMID: 35889819; PMCID: PMC9318754.
• Hamasaki T, Kashiwagi T, Komatsu T, Kabayama S, Nakamichi N, Teruya K, Shirahata S. A new colorimetric method for determining antioxidant levels using 3,5-dibromo-4-nitrosobenzene sulfonate (DBNBS). MethodsX. 2022 Jul 28;9:101797. doi: 10.1016/j.mex.2022.101797. PMID: 35958099; PMCID: PMC9358457.
• Ledrhem M, Nakamura M, Obitsu M, Hirae K, Kameyama J, Bouamama H, Gadhi C, Katakura Y. Essential Oils Derived from Cistus Species Activate Mitochondria by Inducing SIRT1 Expression in Human Keratinocytes, Leading to Senescence Inhibition. Molecules. 2022 Mar 22;27(7):2053. doi: 10.3390/molecules27072053. PMID: 35408452; PMCID: PMC9000612.
• Fujiki T, Matsumoto SE, Kishihara K, Katakura Y. Age-related functional decline of human B cells. Cytotechnology. 2022 Apr;74(2):319-327. doi: 10.1007/s10616-021-00513-z. Epub 2022 Jan 24. PMID: 35464165; PMCID: PMC8975901.
• Ieiri H, Kameda N, Naito J, Kawano T, Nishida N, Takahashi M, Katakura Y. Paramylon extracted from Euglena gracilis EOD-1 augmented the expression of SIRT1. Cytotechnology. 2021 Oct;73(5):755-759. doi: 10.1007/s10616-021-00494-z. Epub 2021 Sep 15. PMID: 34629749; PMCID: PMC8492802.
• Ogawa M, Udono M, Teruya K, Uehara N, Katakura Y. Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion. Nutrients. 2021 Jun 18;13(6):2087. doi: 10.3390/nu13062087. PMID: 34207142; PMCID: PMC8234638.
• Inotsuka R, Uchimura K, Yamatsu A, Kim M, Katakura Y. γ-Aminobutyric acid (GABA) activates neuronal cells by inducing the secretion of exosomes from intestinal cells. Food Funct. 2020 Oct 21;11(10):9285-9290. doi:10.1039/d0fo01184c. PMID: 33048090.
• Kubo C, Ogawa M, Uehara N, Katakura Y. Fisetin Promotes Hair Growth by Augmenting TERT Expression. Front Cell Dev Biol. 2020 Oct 15;8:566617. doi:10.3389/fcell.2020.566617. PMID: 33178686; PMCID: PMC7593534.
• Teruya K, Kusumoto Y, Eto H, Nakamichi N, Shirahata S. Selective Suppression of Cell Growth and Programmed Cell Death-Ligand 1 Expression in HT1080 Fibrosarcoma Cells by Low Molecular Weight Fucoidan Extract. Mar Drugs. 2019 Jul 19;17(7). pii: E421. doi: 10.3390/md17070421.
• Sugihara Y, Onoue S, Tashiro K, Sato M, Hasegawa T, Katakura Y. Carnosine induces intestinal cells to secrete exosomes that activate neuronal cells. PLoS One. 2019 May 28;14(5):e0217394. doi: 10.1371/journal.pone.0217394.
• Hata J, Ohara T, Katakura Y, Shimizu K, Yamashita S, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Kitazono T, Kuhara S, Ninomiya T. Association Between Serum β-Alanine and Risk of Dementia. Am J Epidemiol. 2019 Sep 1;188(9):1637-1645. doi: 10.1093/aje/kwz116.
• Tan H, Zhao C, Zhu Q, Katakura Y, Tanaka H, Ohnuki K, Shimizu K. Ursolic Acid Isolated from the Leaves of Loquat ( Eriobotrya japonica) Inhibited Osteoclast Differentiation through Targeting Exportin 5. J Agric Food Chem. 2019 Mar 27;67(12):3333-3340. doi: 10.1021/acs.jafc.8b06954.
• Harada G, Onoue S, Inoue C, Hanada S, Katakura Y. Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells. Cytotechnology. 2018 Dec;70(6):1707-1712. doi: 10.1007/s10616-018-0246-0.
• Hamano M, Haraguchi Y, Sayano T, Zyao C, Arimoto Y, Kawano Y, Moriyasu K, Udono M, Katakura Y, Ogawa T, Kato H, Furuya S. Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3-phosphoglycerate dehydrogenase-deficient fibroblasts. FEBS Open Bio. 2018 May 8;8(6):914-922. doi: 10.1002/2211-5463.12429. eCollection 2018 Jun.
• Ding Q, Tanigawa K, Kaneko J, Totsuka M, Katakura Y, Imabayashi E, Matsuda H, Hisatsune T. Anserine/Carnosine Supplementation Preserves Blood Flow in the Prefrontal Brain of Elderly People Carrying APOE e4. Aging Dis. 2018 Jun 1;9(3):334-345. doi: 10.14336/AD.2017.0809. eCollection 2018 Jun.
• Chong Z, Matsuo H, Kuroda M, Yamashita S, Parajuli GP, Manandhar HK, Shimizu K, Katakura Y. Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes. Cytotechnology. 2018 Jun;70(3):1001-1008. doi: 10.1007/s10616-018-0229-1. Epub 2018 Jun 2.
• Takahashi H, Kawaguchi M, Kitamura K, Narumiya S, Kawamura M, Tengan I, Nishimoto S, Hanamure Y, Majima Y, Tsubura S, Teruya K, Shirahata S. An Exploratory Study on the Anti-inflammatory Effects of Fucoidan in Relation to Quality of Life in Advanced Cancer Patients. Integr Cancer Ther. 2018 Jun;17(2):282-291. doi: 10.1177/1534735417692097.
• Kadooka K, Sato M, Matsumoto T, Kuhara S, Katakura Y, Fujimura T. Pig testis extract augments adiponectin expression and secretion through the peroxisome proliferator-activated receptor signaling pathway in 3T3-L1 adipocytes. Cytotechnology. 2018 Jun;70(3):983-992. doi: 10.1007/s10616-018-0213-9. Epub 2018 Mar 26.
• Yamashita S, Sato M, Matsumoto T, Kadooka K, Hasegawa T, Fujimura T, Katakura Y. Mechanisms of carnosine-induced activation of neuronal cells. Biosci Biotechnol Biochem. 2018 Apr;82(4):683-688. doi: 10.1080/09168451.2017.1413325. Epub 2017 Dec 11.
• Togo Y, Higuchi Y, Katakura Y, Takegawa K. Early endosome motility mediates α-amylase production and cell differentiation in Aspergillus oryzae. Sci Rep. 2017 Nov 17;7(1):15757. doi: 10.1038/s41598-017-16163-1.
• Katakura Y, Totsuka M, Imabayashi E, Matsuda H, Hisatsune T. Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine CCL24 in Peripheral Blood Mononuclear Cells from Elderly People. Nutrients. 2017 Oct 31;9(11). pii: E1199. doi: 10.3390/nu9111199.
• Inoue C, Zhao C, Tsuduki Y, Udono M, Wang L, Nomura M, Katakura Y. SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes. NPJ Aging Mech Dis. 2017 Aug 30;3:11. doi: 10.1038/s41514-017-0011-1. eCollection 2017.
• Sayano T, Kawano Y, Kusada W, Arimoto Y, Esaki K, Hamano M, Udono M, Katakura Y, Ogawa T, Kato H, Hirabayashi Y, Furuya S. Adaptive response to l-serine deficiency is mediated by p38 MAPK activation via 1-deoxysphinganine in normal fibroblasts. FEBS Open Bio. 2016 Mar 3;6(4):303-16. doi: 10.1002/2211-5463.12038. eCollection 2016 Apr.
• Hisatsune T, Kaneko J, Kurashige H, Cao Y, Satsu H, Totsuka M, Katakura Y, Imabayashi E, Matsuda H. Effect of Anserine/Carnosine Supplementation on Verbal Episodic Memory in Elderly People. J Alzheimers Dis. 2016;50(1):149-59. doi: 10.3233/JAD-150767.
• Fujii, K., Abe, K., Kadooka, K., Matsumoto, T., Katakura, Y., Carnosine activates the CREB pathway in Caco-2 cells. Cytotechnology 69(3):523-527 (2017). doi: 10.1007/s10616-017-0089-0.
• Hamasaki, T., Harada, G., Nakamichi, N., Kabayama, S., Teruya, K., Fugetsu, B., Gong, W., Sakata, I., Shirahata, S., Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water. PLoS ONE. 12(2) e0171192 (2017). doi: 10.1371/journal.pone.0171192.
• Zhao, C., Sakaguchi, T., Fujita, K., Ito, H., Nishida, N., Nagatomo, A., Tanaka-Azuma, Y., Katakura, Y., Pomegranate-Derived Polyphenols Reduce Reactive Oxygen Species Production via SIRT3-Mediated SOD2 Activation. Oxid. Med. Cell Longev. 2016:2927131 (2016).
• Yamashita, S., Fujii, K., Zhao, C., Takagi, H., Katakura, Y., Involvement of the NFX1-repressor complex in PKC-δ-induced repression of hTERT transcription. J. Biochem. 160(5):309-313 (2016).
• Udono, M., Fujii, K., Harada, G., Tsuzuki, Y., Kadooka, K., Zhang, P., Fujii, H., Amano, M., Nishimura, S., Tashiro, K., Kuhara, S., Katakura, Y., Impaired ATP6V0A2 expression contributes to Golgi dispersion and glycosylation changes in senescent cells. Sci. Rep. 5:17342 (2015). doi: 10.1038/srep17342.
• Tan, H., Ashour, A., Katakura, Y., Shimizu, K., A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica). Phytomedicine. 22(4):498-503 (2015). doi: 10.1016/j.phymed.2015.03.002.
• Mira, A., Yamashita, S., Katakura, Y., Shimizu, K. In vitro neuroprotective activities of compounds from Angelica shikokiana Makino. Molecules. 20(3):4813-4832 (2015). doi: 10.3390/molecules20034813.
• Inoue, C., Kozaki, T., Morita, Y., Shirouchi, B., Fukami, K., Shimizu, K., Sato, M., Katakura, Y. Kibizu concentrated liquid suppresses the accumulation of lipid droplets in 3T3-L1 cells. Cytotechnology 67(4): 721-5 (2015).
• Kadooka, K., Fuji, K., Matsumoto, T., Sato, M., Morimatsu, F., Tashiro, K., Kuhara, S., Katakura, Y. Mechanisms and consequences of carnosine-induced activation of intestinal epithelial cells. J. Funct. Foods 13, 32-37 (2015).
• Kashiwagi, T., Yan, H., Hamasaki, T., Kinjo, T., Nakamichi, N., Teruya, K., Kabayama, S., Shirahata, S. Electrochemically reduced water protects neural cells from oxidative damage. Oxid. Med. Cell Longev. 2014:869121 (2014). doi: 10.1155/2014/869121.
• Hamasaki, T., Nakamichi, N., Teruya, K., Shirahata, S. Removal efficiency of radioactive cesium and iodine ions by a flow-type apparatus designed for electrochemically reduced water production. PLoS One. 9(7): e102218 (2014). doi: 10.1371/journal.pone.0102218.
• Fujii, K., Fujiki, T., Koiso, A., Hirakawa, K., Yamashita, M., Matsumoto, T., Hasegawa, T., Morimatsu, F., Katakura, Y. Identification of anti-allergic lactic acid bacteria that suppress Ca²⁺ influx and histamine release in human basophilic cells J. Funct. Foods (in press). doi: 10.1016/j.jff.2014.07.006.
• Harada, G., Neng, Q., Fujiki, T., Katakura, Y. Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast. J. Biochem. 156(5), 283-290 (2014). doi: 10.1093/jb/mvu040
• Yamashita, S., Ogawa, K., Ikei, T., Fujiki., T, Katakura, Y. FOXO3a Potentiates hTERT Gene Expression by Activating c-MYC and Extends the Replicative Life-Span of Human Fibroblast. PLoS One. 9(7) e101864 (2014). doi: 10.1371/journal.pone.0101864.
• Ashour, A., El-Sharkawy, S., Amer, M., Abdel Bar, F., Katakura, Y., Miyamoto, T., Toyota, N., Bang, T.H., Kondo, R., Shimizu, K. Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs. Bioorg. Med. Chem. 22(1):211-220 (2014). doi: 10.1016/j.bmc.2013.11.034.
• Yamashita, M., Harada, G., Matsumoto, S.-E., Aiba, Y., Ichikawa, A., Fujiki, T., Udono, M., Kabayama, S., Yoshida, T., Zhang, P., Fujii, H., Shirahata, S., Katakura, Y. Suppression of immunoglobulin production in human peripheral blood mononuclear cells by monocytes via secretion of heavy-chain ferritin. Immunobiology 219 (2), 149-157 (2014). doi: 10.1016/j.imbio.2013.08.011
• Hai Bang, T., Suhara, H., Doi, K., Ishikawa, H., Fukami, K., Parajuli, G.P., Katakura, Y., Yamashita, S., Watanabe, K., Adhikari, M.K., Manandhar, H.K., Kondo, R., Shimizu, K. Wild mushrooms in Nepal: Some potential candidates as antioxidant and ACE-inhibition sources. Evidence-based Complementary and Alternative Medicine 2014, Article ID 195305 (2014). doi: 10.1155/2014/195305
• Tomimatsu, K., Shirahata, S. Antigen-specific in vitro immunization: A source for human monoclonal antibodies. Methods in Molecular Biology 1060, 297-307 (2014). doi: 10.1007/978-1-62703-586-6-15
• Harada, G., Matsumoto, S.-E., Yamashita, M., Fujii, K., Shirahata, S., Katakura, Y. In vitro immunization of Epstein-Barr virus-immortalized B cells augments antigen-specific antibody production. Cytotechnology 65 (6), 979-983 (2013). doi: 10.1007/s10616-013-9596-9
• Yamamoto, K., Ichinose, H., Aso, Y., Udono, M., Katakura, Y. Upregulation of cytochrome p450s following exposure of the silkmoth, Bombyx mori to insecticides. Journal of Insect Biotechnology and Sericology 82 (2), 33-38 (2013). doi: 10.11416/jibs.82.2_033
• Koguma, I., Yamashita, S., Sato, S., Okuyama, K., Katakura, Y. Novel purification method of human immunoglobulin by using a thermo-responsive protein A. Journal of Chromatography A 1305, 149-153 (2013). doi: 10.1016/j.chroma.2013.07.015
• Ko, Y.-J., Kim, H.-H., Kim, E.-J., Katakura, Y., Lee, W.-S., Kim, G.-S., Ryu, C.-H. Piceatannol inhibits mast cell-mediated allergic inflammation. International Journal of Molecular Medicine 31 (4), 951-958 (2013). doi: 10.3892/ijmm.2013.1283
• Tomimatsu, K., Matsumoto, S.-E., Tanaka, H., Yamashita, M., Nakanishi, H., Teruya, K., Kazuno, S., Kinjo, T., Hamasaki, T., Kusumoto, K.-I., Kabayama, S., Katakura, Y., Shirahata, S. A rapid screening and production method using a novel mammalian cell display to isolate human monoclonal antibodies. Biochemical and Biophysical Research Communications 441 (1), 59-64 (2013). doi: 10.1016/j.bbrc.2013.10.007
• Nakanishi, H., Hamasaki, T., Kinjo, T., Yan, H., Nakamichi, N., Kabayama, S., Teruya, K., Shirahata, S. Low concentration platinum nanoparticles effectively scavenge reactive oxygen species in rat skeletal L6 cells. Nano Biomedicine and Engineering 5 (2), 76 - 85 (2013). doi: 10.5101/nbe.v5i2.p76-85
• Teruya, K., Myojin-Maekawa, Y., Shimamoto, F., Watanabe, H., Nakamichi, N., Tokumaru, K., Tokumaru, S., Shirahata, S. Protective effects of the fermented milk Kefir on X-ray irradiation-induced intestinal damage in B6C3F1 mice. Biol. Pharm. Bull. 36(3), 352-359 (2013).
• Zhang, Z., Teruya, K., Eto, H., Shirahata, S. Induction of apoptosis by low-molecular-weight fucoidan through calcium- and caspase-dependent mitochondrial pathways in MDA-MB-231 breast cancer cells. Biosci. Biotechnol. Biochem. 77(2),235-242 (2013).
• Zhang, Z., Teruya, K., Yoshida, T., Eto, H., Shirahata, S. Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in MDA-MB-231 and MCF-7 breast cancer cells. Mar. Drugs. 11(1), 81-98 (2013).
• Spulber, S., Edoff, K., Hong, L., Morisawa, S., Shirahata, S., Ceccatelli, S. Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice. PLoS ONE, 7(7), e42078 (2012).
• Kinjo, T., Ye, J., Yan, H., Hamasaki, T., Nakanishi, H., Toh, K., Nakamichi, N., Kabayama, S., Teruya, K., Shirahata, S. Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells. Cytotechnol., 64 (3) 357-371 (2012).
• Udono, M., Kadooka, K., Yamashita, S., Katakura, Y. Quantitative analysis of cellular senescence phenotypes using an imaging cytometer. Methods. 56 (3), 383-388 (2012).
• Li, Y., Hamasaki, T., Teruya, K., Nakamichi, N., Gadek, Z., Kashiwagi, T., Yan, H., Kinjo, T., Komatsu, T., Ishii, Y., Shirahata, S. Suppressive effects of natural reduced waters on alloxan-induced apoptosis and type 1 diabetes mellitus. Cytotechnol.,  64 (3) 281-297 (2012).
• Shirahata, S., Hamasaki, T., Teruya, K. Advanced research on the health benefit of reduced water. Trends in Food Science and Technology, 23, 124-131 (2012).
• Yamashita, S., Ogawa, K., Ikei, T., Udono, M., Fujiki, T., Katakura, Y. SIRT1 prevents replicative senescence of normal human umbilical cord fibroblast through potentiating the transcription of human telomerase reverse transcriptase gene. Biochem. Biophys. Res. Commun., 417, 630-634 (2012).
• Kadooka, K., Imahayashi, A., Koiso, A., Yamashita, M., Teruya, K., Matsumoto, T., Hasegawa, T., Morimatsu, F., Katakura, Y. Establishment of a novel method of screening anti-Allergic lactic acid bacteria. Biosci. Biotech. Biochem., 75, 1016-1018 (2011).
• Li, Y., Hamasaki, T., Nakamichi, N., Kashiwagi, T., Komatsu, T., Ye, J., Teruya, K., Abe, M., Yan, H., Kinjo, T., Kabayama, S., Kawamura, M., Shirahata, S. Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. Cytotechnol., 63, 119-131 (2011).
• Yamamoto, K., Teshiba, S., Shigeoka, Y., Aso, Y., Banno, Y., Fujiki, T., Katakura, Y. Characterization of an omega-class glutathione S-transferase in the stress response of the silkmoth Insect. Mol. Biol., 20, 379-386 (2011).
• Yamamoto, K., Tsuji, Y., Aso, Y., Hamasaki, T., Shirahata, S., Katakura, Y. Effect of diazinon exposure on antioxidant reactions in the silkmoth, Bombyx mori. J. Appl. Entomol., 135, 320-325 (2011).
• Yan, H., Kinjo, T., Tian, H., Hamasaki, T., Teruya, K., Kabayama, S., Shirahata, S. Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water-participation of pt nanoparticles. Biosci. Biotech. Biochem., 75, 1295-1299 (2011).
• Zhang, Z., Teruya, K., Eto, H., Shirahata, S. Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ros-dependent JNK activation and mitochondria-mediated pathways. PLoS One, 6 (11), e27441 (2011).
• Tong, L. -T, Katakura, Y., Kawamura, S., Baba, S., Tanaka, Y., Udono, M., Kondo, Y., Nakamura, K., Imaizumi, K., Sato, M. Effects of Kurozu concentrated liquid on adipocyte size in rats. Lipids Health Dis. Nov 23; 9: 134 (2010).
• Yan, H., Tian, H., Kinjo, T., Hamasaki, T., Tomimatsu, K., Nakamichi, N., Teruya, K., Kabayama, S., Shirahata, S. Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water. Biosci. Biotech. Biochem., 74, 2011-2015 (2010).
• Fujiki, T., Udono, M., Kotake, Y., Yamashita, M., Shirahata, S., Katakura, Y. NFAT5 regulates transcription of the mouse telomerase reverse transcriptase gene. Exp. Cell Res., 316, 3342-3350 (2010).
• Fujiki, T., Tsuji, A., Matsumoto, S.E., Yamashita, M., Teruya, K., Shirahata, S., Katakura, Y. Generation of a human anti-tumor necrosis factor-α monoclonal antibody by in vitro immunization with a multiple antigen peptide. Biosci. Biotech. Biochem., 74, 1836-1840 (2010).
• Fujiki, T., Udono, M., Kadooka, K., Yamashita, S., Miura, T., Shirahata, S., Katakura, Y. Regulatory mechanisms of human and mouse telomerase reverse transcriptase gene transcription: Distinct dependency on c-Myc. Cytotechnol., 62, 333-339 (2010).
• Tomimatsu, K., Matsumoto, S., Yamashita, M., Teruya, K., Katakura, Y., Kabayama, Shirahata, S. Production of human monoclonal antibodies against FcεRIα by a method combining in vitro immunization with phage display. Biosci. Biotech. Biochem., 73, 1465-1469 (2009).
• Katakura, Y., Udono M., Katsuki K., Nishide H., Tabira Y., Ikei T., Yamashita M., Fujiki T., Shirahata S. Protein kinase C δ plays a key role in cellular senescence programs of human normal diploid cells. J. Biochem., 146, 87-93 (2009).
• Yoshizaki, K., Fujiki, T., Tsunematsu, T., Yamashita, M., Udono, M., Shirahata, S., Katakura, Y. Pro-senescent effect of hydrogen peroxide on cancer cells and its possible application to tumor suppression. Biosci. Biotech. Biochem. 73, 311-315 (2009).
• Hamasaki, T., Kashiwagi, T., Imada, T., Nakamichi, N., Aramaki, S., Toh, K., Morisawa, S., Shimakoshi, H., Hisaeda, Y., Shirahata, S. Kinetic analysis of superoxide anion radical- and hydroxyl radical-scavenging activities of platinum nanoparticles. Langmuir, 24, 7354-7364 (2008)
• Jung, Y.-S., Matsumoto, S., Katakura, Y., Yamashita, M., Tomimatsu, K., Kabayama, S., Teruya, K., Shirahata, S. Generation of human monoclonal antibodies against Propionibacterium acnes by applying the phage display method to human peripheral blood mononuclear cells immunized in vitro. Cytotechnol., 57, 169-175 (2008).
• Udono, M., Fujiki, T., Yamashita, M., Katsuki, K., Funata, M., Imada, Y., Yoshizaki, K., Shirahata, S., Katakura, Y. Construction of a regulatable cancer-specific adenoviral expression system using human telomerase reverse transcriptase gene promoter. Biosci. Biotech. Biochem. 72, 1638-1641 (2008).
• Matsumoto, S., Yamashita, M., Katakura, Y., Aiba, Y., Tomimatsu, K., Kabayama, S., Teruya, K., Shirahata, S. A rapid and efficient strategy to generate antigen-specific human monoclonal antibody by in vitro immunization and the phage display method. J. Immunol. Methods., 332, 2-9 (2008).
• Ye, J., Li, Y., Hamasaki, T., Nakamichi, N., Komatsu, T., Kashiwagi, T., Teruya, K., Nishikawa, R., Kawahara, T., Osada, K., Toh, K., Abe, M., Tian, H., Kabayama, S., Otsubo, K., Morisawa, S., Katakura, Y., Shirahata, S. Inhibitory effect of electrolyzed reduced water on tumor angiogenesis. Biol. Pharm. Bull., 31, 19-26 (2008).
• Fujiki, T., Miura, T., Maura, M., Shiraishi, H., Nishimura, S., Imada, Y., Uehara, N., Tashiro, K., Shirahata, S., Katakura, Y. TAK1 represses transcription of the human telomerase reverse transcriptase gene. Oncogene, 26, 5258-5266 (2007).
• Yamashita, M., Katakura, Y., Shirahata, S. Recent advances in the generation of human monoclonal antibody. Cytotechnol., 55, 55-60 (2007).
• Jung, Y.-S., Matsumoto, S., Yamashita, M., Tomimatsu, K., Teruya, K., Katakura, Y., Shirahata, S. Propionibacterium acnes acts as an adjuvant in in vitro immunization of human peripheral blood mononuclear cells. Biosci. Biotech. Biochem. 71, 1963-1969 (2007) .
• Ye, J., Li, Y., Hamasaki, T., Nakamichi, N., Kawahara, T., Osada, K., Teruya, K., Kato, Y., Toh, K., Abe, M., Katakura, Y., Noguchi, K., Shirahata, S. Catalyser-21™, a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis. Cytotechnol. 55, 61-70 (2007).
• Tamura, T., Tomimatsu, K., Katakura, Y., Yamashita, M., Matsumoto, S. E., Aiba, Y., Jung, Y. S., Abe, Y., Fujiki, T., Teruya, K., and Shirahata, S. Anti-peptide antibody production elicited by in vitro immunization of human peripheral blood mononuclear cells. Biosci. Biotech. Biochem., 71, 2871-2875 (2007).
• Yamashita, M., Katakura, Y., Aiba, Y., Matsumoto, S. E., Morihara, K., Teruya, K., Ichikawa, A., Shirahata, S. Involvement of IL-10 in the suppression of antibody production by in vitro immunized peripheral blood mononuclear cells. Cytotechnol., 55, 71-77 (2007).
• Matsumoto, S., Yamashita, M., Katakura, Y., Noguchi, E., Aiba, Y., Ichikawa, A., Teruya, K., Shirahata., S. In vitro immunization can elicit the expansion of diverse repertoire of B cells from peripheral blood mononuclear cells. Cytotechnol., 52, 227-233 (2006).
• Inoue, Y., Kawahara, H., Shirahata, S., Sugimoto, Y. Retinoic acid improves a hybridoma culture in a fructose-based medium by up-regulation of fructose incorporation via retinoid nuclear receptors. Biosci. Biotech. Biochem., 70, 2248-2253 (2006).
• Katakura, Y. Molecular basis for the cellular senescence program and its application to anticancer therapy. Biosci. Biotech. Biochem., 70, 1076-1081 (2006).
• Aiba, Y., Yamashita, M., Katakura, Y., Furukawa, Y., Matsumoto, S., Tomimatsu, K., Teruya, K., Shirahata, S. Identification of genes involved in the suppression of antibody production from human peripheral blood lymphocytes. Biosci. Biotech. Biochem., 70, 996-970 (2006).
• Ye, J., Li, Y.-P., Teruya, K., Katakura, Y., Ichikawa, A., Eto, H., Hosoi, M., Hosoi, M., Nishimoto, S., Shirahata, S. Enzyme-digested fucoidan extracts derived from seaweed Mozuku of Cladosiphon novae-caledoniae kylin inhibit invasion and angiogenesis of tumor cells. Cytotechnol. 47, 117-126 (2005).
• Nishikawa, R., Teruya, K., Katakura, Y., Osada, K., Hamasaki, T., Kashiwagi, T., Komatsu, T., Li, Y.-P., Ye, J., Ichikawa, A., Otsubo, K., Morisawa, S., Xu, Q.-H., Shirahata, S. Electrolyzed reduced water supplemented with platinum nanoparticles suppresses promotion of two-stage cell transformation. Cytotechnol. 47, 97-105 (2005).
• Teruya, K., Daimon, Y., Dong, X.-Y., Katakura, Y., Miura, T., Ichikawa, A., Fujiki, T., Yamashita, M., Mori, T., Ohashi, H., Shirahata S. An approach to further enhance the cellular productivity of exogenous protein hyper-producing Chinese hamster ovary (CHO) cells. Cytotechnol. 47, 29-36 (2005).
• Katakura, Y., Yoshizaki, K., Yasuda, T., Tsunematsu, T., Uehara, N., Miura, T., Fujiki, T., Shirahata, S.　 Functional impairment of telomerase in sublines derived from human lung adenocarcinoma exposed to mild oxidative stress. Biochem. Biophys. Res. Commun. 334, 450-459 (2005).
• 加藤祐子，太田雅也，亀井恭平，脇田久伸，河原岳志，山野雄一郎，濱崎武記，照屋輝一郎，長田和浩，西川竜平，野口克己，白畑實隆．IL-12誘導活性を示す天然葉緑土由来ミネラル水中の複合糖質の構造解析．分析化学　54, 391-397 (2005).
• Xu QH, Katakura Y, Yamashita M, Fang S, Tamura T, Matsumoto S, Aiba Y, Teruya K, Osada K, Nishikawa R, Shirahata S. IL-10 augments antibody production in in vitro immunized lymphocytes by inducing a Th2-type response and B cell maturation. Biosci. Biotech. Biochem. 68: 2279-2284 (2004).
• Dong XY, Teruya K, Katakura Y, Zhang YP, Miura T, Daimon Y, Mori T, Ohashi H, Shirahata S. A hybrid system using both promoter activation and gene amplification for establishing exogenous protein hyper-producing cell lines. Cytotechnol. 43: 11-17 (2003).
• Matsuu M, Shichijo K, Okaichi K, Wen CY, Fukuda E, Nakashima M, Nakayama T, Shirahata S, Tokumaru S, Sekine I.  The protective effect of fermented milk kefir on radiation-induced apoptosis in colonic crypt cells of rats.  J Radiat Res. 44: 111-115 (2003).
• Katakura Y, Nakata E, Tabira Y, Miura T, Teruya K, Tsuchiya T, Shirahata S.  Decreased tumorigenicity in vivo when transforming growth factor beta treatment causes cancer cell senescence.  Biosci Biotechnol Biochem. 67: 815-821 (2003).
• Inoue Y, Shirahata S.  Increased antibody production by retinoids is related to the fusion partner of human hybridomas.  Biosci Biotechnol Biochem. 66: 215-217 (2002).
• Teruya K, Zhang YP, Katakura Y, Shirahata S.  A regulatable selective system facilitates isolation of heterologous protein hyper-producing mammalian cells without gene amplification.  Cytotechnol. 40: 13-22 (2002).
• Shim SY, Ichikawa A, Yamashita M, Katakura Y, Teruya K, Mochizuki Y, Tobinaga E, Shirahata S.  Construction of an in vitro allergy reaction evaluation system using human leukemia cell lines.  Cytotechnol. 40: 75-83 (2002).
• Teruya K, Yamashita M, Tominaga R, Nagira T, Shim SY, Katakura Y, Tokumaru S, Tokumaru K, Barnes D, Shirahata S.  Fermented milk, Kefram-Kefir enhances glucose uptake into insulin-responsive muscle cells.  Cytotechnol. 40: 107-116 (2002).
• Nagira T, Narisawa J, Teruya K, Katakura Y, Shim SY, Kusumoto K, Tokumaru S, Tokumaru K, Barnes DW, Shirahata S.  Suppression of UVC-induced cell damage and enhancement of DNA repair by the fermented milk, Kefir.  Cytotechnol. 40: 125-137 (2002).
• Li YP, Nishimura T, Teruya K, Maki T, Komatsu T, Hamasaki T, Kashiwagi T, Kabayama S, Shim SY, Katakura Y, Osada K, Kawahara T, Otsubo K, Morisawa S, Ishii Y, Gadek Z, Shirahata S.  Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species.  Cytotechnol. 40: 139-149 (2002).
• Yamashita M, Katakura Y, Shim SY, Matsumoto S, Tamura T, Morihara K, Aiba Y, Teruya K, Tsuchiya T, Shirahata S.  Different individual immune responses elicited by in vitro immunization.  Cytotechnol. 40: 161-165 (2002).
• Miura T, Katakura Y, Seto P, Zhang YP, Teruya K, Nishimura E, Kato M, Hashizume S, Shirahata S.  Availability of oncogene activated production system for mass production of light chain of human antibody in CHO cells.  Cytotechnol. 35: 9-16 (2001).
• Uehara N, Katakura Y, Miura T, Shirahata S.  Subtractive screening of genes involved in cellular senescence.  Cytotechnol. 35: 35-42 (2001).
• Kawakatsu H, Ide S, Okuda Y, Shirahata S.  Hydroxyapatite-pulp composite fiber sheet bed: A new material for the immobilization of CHO-K1 cells.  Cytotechnol. 35: 65-72 (2001).
• Ichikawa A, Shim SY, Katakura Y, Teruya K, Hashizume S, Shirahata S.  Molecular analysis of cross-reactive human monoclonal antibody AE6F4 generated by in vitro immunization: Epitope mapping of AE6F4 antibody on 14-3-3 family proteins and cytokeratin 8.  Cytotechnol. 36: 101-107 (2001).
• Shim SY, Katakura Y, Ichikawa A, Teruya K, Matsuda T, Shirahata S.  Epitope analysis of human monoclonal antibody specific for rice allergenic protein generated by in vitro immunization.  Cytotechnol. 36: 109-115 (2001).
• Miura T, Katakura Y, Yamamoto K, Uehara N, Tsuchiya T, Kim EH, Shirahata S.  Neural stem cells lose telomerase activity upon differentiating into astrocytes.  Cytotechnol. 36: 137-144 (2001).
• Kawahara T, Ichikawa A, Katakura Y, Teruya K, Yoshida T, Kikuchi M, Kamei M, Hashizume S, Shirahata S.  Establishment of hybridomas producing cancer specific human antibodies from B cell line derived from PBL of a patient with adult T cell leukemia.  Cytotechnol. 36: 171-177 (2001).
• Yamashita M, Ichikawa A, Katakura Y, Mochizuki Y, Teruya K, Kim EH, Shirahata S.  Induction of basophilic and eosinophilic differentiation in the human leukemic cell line KU812.  Cytotechnol. 36: 179-186 (2001).
• Inoue Y, Kawamoto S, Shoji M, Hashizume S, Teruya K, Katakura Y, Shirahata S.  Properties of ras-amplified recombinant BHK-21 cells in protein-free culture.  Cytotechnol. 33: 21-26 (2000).
• Kanegawa K, Harada H, Myouga H, Katakura Y, Shirahata S, Kamei Y.  Telomerase inhibiting activity in vitro from natural resources, marine algae extracts.  Cytotechnol. 33: 221-227 (2000).
• Kawamoto S, Iemura N, Inoue Y, Katakura Y, Shirahata S.  Effect of 14-3-3 protein induction on cell proliferation of A549 human lung adenocarcinoma.  Cytotechnol. 33: 253-257 (2000).
• Kusumoto K, Shirahata S, Kamei Y.  Purification and characterization of alpha-D-galactosidase produced by ADG cell line established from abalon digestive gland.  Cytotechnol. 33: 47-52 (2000).
• Alam S, Katakura Y, Yoshida H, Kim EH, Shirahata S.  Improvement of a method to reproducibly immortalize human T cells by oncogene transfection.  Cytotechnol. 33: 71-81 (2000).
• Inoue Y, Fujisawa M, Shoji M, Hashizume S, Katakura Y, Shirahata S.  Enhanced antibody production of human-human hybridomas by retinoic acid.  Cytotechnol. 33: 83-88 (2000).
• Inoue Y, Arita N, Teruya K, Katakura Y, Shirahata S.  Efficient production of recombinant human erythropoietin by replenishment of microcarriers in the hollow fiber culture cassette.  Biosci Biotechnol Biochem. 63: 1624-1626 (1999).
• Nishimura E, Mochizuki K, Kato M, Hashizume S, Haruta H, Shirahata S, Suzuki T, Nomoto K, Kanaya K, Kusakabe K.  Recombinant light chain of human monoclonal antibody HB4C5 as a potentially useful lung cancer-targeting vehicle.  Hum Antibodies. 9: 111-124 (1999).
• Katakura Y, Nakata E, Miura T, Shirahata S.  Transforming growth factor beta triggers two independent-senescence programs in cancer cells.  Biochem Biophys Res Commun. 255: 110-115 (1999).
• Katakura Y, Seto P, Miura T, Ohashi H, Teruya K, Shirahata S.  Productivity enhancement of recombinant protein in CHO cells via specific promoter activation by oncogenes.  Cytotechnol. 31: 103-109 (1999).
• Ichikawa A, Katakura Y, Teruya K, Hashizume S, Shirahata S.  In vitro immunization of human peripheral blood lymphocytes: establishment of B cell lines secreting IgM specific for cholera toxin B subunit from lymphocytes stimulated with IL-2 and IL-4.  Cytotechnol. 31: 131-139 (1999).
• Alam S, Katakura Y, Shirahata S.  Establishment of human T cell clones exhibiting natural killer-like activity.  Cytotechnol. 31: 171-176 (1999).
• Inoue Y, Fujisawa M, Kawamoto S, Shoji M, Hashizume S, Fujii M, Katakura Y, Shirahata S.  Effectiveness of vitamin A acetate for enhancing the production of lung cancer specific monoclonal antibodies.  Cytotechnol. 31: 77-83 (1999).
• Shirahata S, Katakura Y, Teruya K.  Cell hybridization, hybridomas, and human hybridomas.  Methods Cell Biol. 57: 111-145 (1998).
• Katakura Y, Alam S, Shirahata S.  Immortalization by gene transfection.  Methods Cell Biol. 57: 69-91 (1998).
• Kabayama S, Osada K, Tachibana H, Katakura Y, Shirahata S.  Enhancing effects of food components on the production of interferon beta from animal cells suppressed by stress hormones.  Cytotechnol. 23: 119-125 (1997).
• Tachibana H, Kim JY, Shirahata S.  Building high affinity human antibodies by altering the glycosylation on the light chain variable region in N-acetylglucosamine-supplemented hybridoma cultures.  Cytotechnol. 23: 151-159 (1997).
• Alam S, Katakura Y, Yoshida H, Kim EH, Shirahata S.  Functional characterization of human T cells immortalized by oncogene transfection.  Cytotechnol. 23: 185-192 (1997).
• Zhang YP, Katakura Y, Seto P, Shirahata S.  Evidence that phosphatidylcholine-specific phospholipase C is a key molecule mediating insulin-induced enhancement of gene expression from human cytomegalovirus promoter in CHO cells.  Cytotechnol. 23: 193-196 (1997).
• Yamaguchi M, Shirai Y, Inouye Y, Shoji M, Kamei M, Hashizume S, Shirahata S.  Changes in monoclonal antibody productivity of recombinant BHK cells immobilized in collagen gel particles.  Cytotechnol. 23: 5-12 (1997).
• Kusumoto K, Shirahata S, Katakuta Y, Murakami H, Kamei Y.  Establishment of an abalone digestive gland cell line secreting various glycosidases in protein-free culture.  Cytotechnol. 24: 169-175 (1997).
• Siripen T, Tachibana H, Katakura Y, Shirahata S.  Improvement of antigen binding ability of human antibodies by light chain shifting.  Cytotechnol. 25: 155-164 (1997).
• Zhang YP, Katakura Y, Ohashi H, Shirahata S.  Efficient and inducible production of human interleukin 6 in Chinese hamster ovary cells using a novel expression system.  Cytotechnol. 25: 53-60 (1997).
• Krungkasem C, Ueda K, Tachibana H, Shirahata S.  Further investigation of the light chain shifting phenomenon: light chain replacement through secondary rearrangement induced by lectin stimulation in the hybridoma cell line HB4C5.  Cytotechnol. 25: 145-154 (1997).
• Bradford CS, Miller AE, Toumadje A, Nishiyama K, Shirahata S, Barnes DW.  Characterization of cell cultures derived from Fugu, the Japanese pufferfish.  Mol Mar Biol Biotechnol. 6: 279-288 (1997).
• Ichikawa A, Tachibana H, Kawamoto S, Kamei M, Honjoh T, Hashizume S, Shirahata S.  Cytokeratin 8 and 19 as antigens recognized by adenocarcinoma-reactive human monoclonal antibody AE6F4.  Hum Antibodies. 8: 195-202 (1997).
• Zhang Y, Katakura Y, Ohashi H, Shirahata S.  An autocatalytic expression system for regulated production of recombinant protein in mammalian cells.  Anal Biochem. 252: 286-292 (1997).
• Haruta H, Tachibana H, Mochizuki K, Hashizume S, Kusakabe K, Shirahata S, Murakami H.  Class-switching of the IgM type anti-adenocarcinoma human antibody HB4C5 into an IgG1 type resulted in the loss of the antigen binding ability.  Hum Antibodies. 8: 137-145 (1997).
• Katakura Y, Yamamoto K, Miyake O, Yasuda T, Uehara N, Nakata E, Kawamoto S, Shirahata S.  Bidirectional regulation of telomerase activity in a subline derived from human lung adenocarcinoma.  Biochem Biophys Res Commun. 237: 313-317 (1997).
• Shirahata S, Kabayama S, Nakano M, Miura T, Kusumoto K, Gotoh M, Hayashi H, Otsubo K, Morisawa S, Katakura Y.  Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.  Biochem Biophys Res Commun. 234: 269-74 (1997).
• Tamai T, Tsujimura K, Shirahata S, Oda H, Noguchi T, Kusuda R, Sato N, Kimura S, Katakura Y, Murakami H.  Development of DNA diagnostic methods for the detection of new fish iridoviral diseases.  Cytotechnol. 23: 211-220 (1997).
• Tachibana H, Ushio Y, Krungkasem C, Shirahata S.  Inducing the loss of immunoglobulin lambda light chain production and the rearrangement of a previously excluded allele in human plasma B cell lines with concanavalin A.  J Biol Chem. 271: 17404-17410 (1996).
• Inoue Y, Lopez LB, Kawamoto S, Arita N, Teruya K, Seki K, Shoji M, Kamei M, Hashizume S, Shiozawa Y, Tachibana H, Ohashi H, Yasumoto K, Nagashima A, Nakahashi H, Suzuki T, Imai T, Nomoto K, Takenoyama M, Katakura Y, Shirahata S.  Production of recombinant human monoclonal antibody using ras-amplified BHK-21 cells in a protein-free medium.  Biosci Biotechnol Biochem. 60: 811-817 (1996).
• Tachibana H, Jiyoun K, Taniguchi K, Ushio Y, Teruya K, Osada K, Inoue Y, Shirahata S, Murakami H.  Modified antigen-binding of human antibodies with glycosylation variations of the light chains produced in sugar-limited human hybridoma cultures.  In Vitro Cell Dev Biol Anim. 32: 178-183 (1996).
• Shoji M, Kawamoto S, Seki K, Teruya K, Setoguchi Y, Mochizuki K, Kato M, Hashizume S, Hanagiri T, Yoshimatsu T, Nakanishi K, Yasumoto K, Nagashima A, Nakahashi H, Suzuki T, Imai T, Shirahata S, Nomoto K, Murakami H.  Lung cancer-reacting human recombinant antibody AE6F4: potential usefulness in the sputum cytodiagnosis.  Hum Antibodies Hybridomas. 7: 27-36 (1996).
• Yanagihara, H., Sakata, R., Shoyama, Y., and Murakami, H., Rapid analysis of small samples containing forskolin using monoclonal antibodies. Planta Medica, 62, 169-72 (1996).
• Kawamoto, S., Hashizume, S., Katakura, Y., Tachibana, H., and Murakami, H., Molecular cloning of yeast cytochrome c-like polypeptide expressed in human lung carcinoma: an antigen recognizable by lung cancer-specific human monoclonal antibody. In Vitro Cellular & Developmental Biology. Animal, 31, 724-9 (1995).
• Kawamoto, S., Shoji, M., Setoguchi, Y., Kato, M., Hashizume, S., Ichikawa, A., Osada, K., Katakura, Y., Tachibana, H., and Murakami, H., Molecular cloning of the 31 kDa cytosolic phospholipase A2, as an antigen recognized by the lung cancer-specific human monoclonal antibody, AE6F4. Cytotechnol., 17, 103-8 (1995).
• Kawamoto S, Inoue Y, Shinozaki Y, Katakura Y, Tachibana H, Shirahata S, Murakami H.  Impaired tumor phenotypes in class II major histocompatibility complex antigen-inducible cells originated from human lung adenocarcinoma.  Biochem Biophys Res Commun. 215: 280-285 (1995).
• Sugahara T, Shirahata S, Sasaki T, Murakami H.  The mode of actions of glyceraldehyde-3-phosphate dehydrogenase identified as an immunoglobulin production stimulating factor.  FEBS Lett. 368: 92-96 (1995).
• Kawamoto S, Hashizume S, Katakura Y, Tachibana H, Shirahata S, Murakami H.  Epitope in cytochrome c from Candida krusei cross-reacts lung cancer-specific human monoclonal antibody HB4C5.  In Vitro Cell Dev Biol Anim. 31: 424-426 (1995).
• Shirahata S, Watanabe J, Teruya K, Yano T, Osada K, Ohashi H, Tachibana H, Kim EH, Murakami H.  E1A and ras oncogenes synergistically enhance recombinant protein production under control of the cytomegalovirus promoter in BHK-21 cells.  Biosci Biotechnol Biochem. 59: 345-347 (1995).
• Teruya K, Yano T, Shirahata S, Watanabe J, Osada K, Ohashi H, Tachibana H, Kim EH, Murakami H.  Ras amplification in BHK-21 cells produces a host cell line for further rapid establishment of recombinant protein hyper-producing cell lines.  Biosci Biotechnol Biochem. 59: 341-344 (1995).
• Yano T, Teruya K, Shirahata S, Watanabe J, Osada K, Tachibana H, Ohashi H, Kim EH, Murakami H.  Ras oncogene enhances the production of a recombinant protein regulated by the cytomegalovirus promoter in BHK-21 cells.  Cytotechnol. 16: 167-178 (1994).
• Teruya K, Shirahata S, Yano T, Seki K, Tachibana H, Ohashi H, Murakami H.  Secretory cell immunoscreening assay--a highly sensitive screening method for secretory cells.  Anal Biochem. 214: 468-473 (1993).
• Tamai T, Shirahata S, Noguchi T, Sato N, Kimura S, Murakami H.  Cloning and expression of flatfish (Paralichthys olivaceus) interferon cDNA.  Biochim Biophys Acta. 1174: 182-186 (1993).
• Tachibana H, Shirahata S, Murakami H.  Human bifunctional antibody generated by heterologous association of heavy and light chains.  Hum Antibodies Hybridomas. 4: 42-46 (1993).
• Kato M, Mochizuki K, Hashizume S, Tachibana H, Shirahata S, Murakami H.  Activity enhancement of a lung cancer-associated human monoclonal antibody HB4C5 by N-deglycosylation.  Hum Antibodies Hybridomas. 4: 9-14 (1993).
• Osada K, Nagira K, Teruya K, Tachibana H, Shirahata S, Murakami H.  Enhancement of interferon-beta production with sphingomyelin from fermented milk.  Biotherapy. 7: 115-123 (1993).
• Okano F, Tachibana H, Akiyama K, Shirahata S, Murakami H.  Immortalization of human T lymphocytes by oncogenes.  Cytotechnol. 11: 205-211 (1993).
• Tamai T, Shirahata S, Sato N, Kimura S, Nonaka M, Murakami H.  Purification and characterization of interferon-like antiviral protein derived from flatfish (Paralichthys olivaceus) lymphocytes immortalized by oncogenes.  Cytotechnol. 11: 121-131 (1993).
• Tachibana H, Shirahata S, Murakami H.  Generation of specificity-variant antibodies by alteration of carbohydrate in light chain of human monoclonal antibodies.  Biochem Biophys Res Commun. 189: 625-632 (1992).
• Tahara T, Shirahata S, Osada K, Tachibana H, Shinohara K, Murakami H.  Stimulation of interferon beta production of cultured cells by phospholipids in foodstuffs.  Biosci Biotechnol Biochem. 56: 1465-1466 (1992).
• Kawahara H, Shirahata S, Tachibana H, Murakami H.  In vitro immunization of human lymphocytes with human lung cancer cell line A549.  Hum Antibodies Hybridomas. 3: 8-13 (1992).
• Sugahara T, Nakajima H, Shirahata S, Murakami H.  Purification and characterization of immunoglobulin production stimulating factor-II beta derived from Namalwa cells.  Cytotechnol. 10: 137-146 (1992).
• Kuroita T, Tachibana H, Ohashi H, Shirahata S, Murakami H.  Growth stimulating activity of heat shock protein 90 alpha to lymphoid cell lines in serum-free medium.  Cytotechnol. 8: 109-117 (1992).
• Shinmoto H, Dosako S, Tachibana H, Shirahata S, Murakami H.  Generation of human-mouse hybridoma secreting human IgM class anti-neocarzinostatin antibody and its application to hybrid hybridoma.  Agric Biol Chem. 55: 2883-2885 (1991).
• Tachibana H, Shirahata S, Kawahara H, Murakami H.  Increased antigen binding strengths of hybrid antibodies produced by human hybrid hybridomas.  Cytotechnol. 7: 1-6 (1991).
• Tachibana H, Akiyama K, Shirahata S, Murakami H.  Altered reactivity of immunoglobulin produced by human-human hybridoma cells transfected by pSV2-neo gene.  Cytotechnol. 6: 219-226 (1991).
• Shirahata S, Tachibana H, Mori T, Seki K, Yamada K, Murakami H.  Changes in specificities of human monoclonal antibodies by introduction of drug-resistance gene into hybridomas.  Agric Biol Chem. 55: 1689-1691 (1991).
• Sugahara T, Shirahata S, Akiyoshi K, Isobe T, Okuyama T, Murakami H.  Immunoglobulin production stimulating factor-II alpha (IPSF-II alpha) is glyceraldehyde-3-phosphate dehydrogenase like protein.  Cytotechnol. 6: 115-120 (1991).
• Eto N, Yamada K, Koga A, Shirahata S, Murakami H.  Establishment and characterization of monoclonal antibodies against Chuzan virus K-47.  Cytotechnol. 6: 13-21 (1991).
• Eto N, Yamada K, Nagamine K, Haramaki K, Shirahata S, Murakami H.  Multiplication of bovine viruses in hamster lung HmLu-1 cells cultured in protein-free medium.  Agric Biol Chem. 55: 1175-1177 (1991).
• Rawson C, Shirahata S, Collodi P, Natsuno T, Barnes D.  Oncogene transformation frequency of nonsenescent SFME cells is increased by c-myc.  Oncogene. 6: 487-489 (1991).
• Yamada K, Matsumura K, Suzaki M, Shirahata S, Murakami H.  Stimulation and inhibition of interferon-beta production of human diploid fibroblasts by foodstuffs.  Agric Biol Chem. 55: 829-832 (1991).
• Eto N, Yamada K, Shito T, Shirahata S, Murakami H.  Development of a protein-free medium with ferric citrate substituting transferrin for the cultivation of mouse-mouse hybridomas.  Agric Biol Chem. 55: 863-865 (1991).
• Yamada K, Ikeda I, Nakajima H, Shirahata S, Murakami H.  Stimulation of proliferation and immunoglobulin production of human-human hybridoma by various types of caseins and their protease digests.  Cytotechnol. 5: 279-285 (1991).
• Sugahara T, Shirahata S, Yamada K, Murakami H.  Purification of immunoglobulin production stimulation factor II alpha derived from Namalwa cells.  Cytotechnol. 5: 255-263 (1991).
• Shinmoto H, Dosako S, Tachibana H, Yamada K, Shirahata S, Murakami H.  Generation of hybrid hybridomas secreting human IgM class hybrid antiricin and antidiphtheria toxin antibodies.  Hum Antibodies Hybridomas. 2: 39-41 (1991).
• Eto N, Yamada K, Koga A, Shirahata S, Murakami H.  Establishment and characterization of monoclonal antibodies against bovine ephemeral fever virus.  Agric Biol Chem. 55: 167-172 (1991).
• Murakami H, Yamada K, Shirahata S, Enomoto A, Kaminogawa S.  Physiological enhancement of immunoglobulin production of hybridomas in serum-free media.  Cytotechnol. 5: 83-94 (1991).
• Kawahara H, Yamada K, Shirahata S, Murakami H.  A new human fusion partner, HK-128, for making human-human hybridomas producing monoclonal IgG antibodies.  Cytotechnol. 4: 139-143. (1990)
• Shinmoto H, Dosako S, Yamada K, Shirahata S, Murakami H.  Purification and some properties of proliferation suppressing factor from human lung adenocarcinoma PC-8. Cytotechnol. 4: 121-126 (1990).
• Shirahata S, Rawson C, Loo D, Chang YJ, Barnes D.  ras and neu oncogenes reverse serum inhibition and epidermal growth factor dependence of serum-free mouse embryo cells.  J Cell Physiol. 144: 69-76 (1990).
• Yamada K, Nagamine K, Shirahata S, Murakami H.  Proliferation-stimulating activity of detergents having oleic acid residues in serum-free culture of mammalian cells.  Agric Biol Chem. 54: 1867-1868 (1990).
• Yamada K, Ikeda I, Maeda M, Shirahata S, Murakami H.  Effect of immunoglobulin production stimulating factors in foodstuffs on immunoglobulin production of human lymphocytes.  Agric Biol Chem. 54: 1087-1089 (1990).
• Toyoda K, Sugahara T, Inouye K, Yamada K, Shirahata S, Murakami H.  Purification and characterization of immunoglobulin production stimulating factor derived from human B lymphoblastoid HO-323 cells.  Cytotechnol. 3: 189-197 (1990).
• Yamada K, Ikeda I, Sugahara T, Hashizume S, Shirahata S, Murakami H.  Stimulation of proliferation and immunoglobulin M production by lactoferrin in human-human and mouse-mouse hybridomas cultures in serum-free conditions.  Cytotechnol. 3 :123-131 (1990).

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