黄麹菌を用いた有用物質生産に向けた分子細胞生物学研究
(樋口准教授)

論文発表

*corresponding author


24. Y. Morita, K. Takegawa, B. M. Collins, Y. Higuchi*

Polarity-dependent expression and localization of secretory glucoamylase mRNA in filamentous fungal cells

Microbiological Research, 282, 127653 (2024)

プレスリリース(2024年3月11日11時)

(bioRxiv, doi: https://doi.org/10.1101/2023.10.12.562120)


23. R. Hiasa, K. Kakimoto, K. Takegawa, Y. Higuchi*

Involvement of AAA ATPase AipA in endocytosis of the arginine permease AoCan1 depending on AoAbp1 in Aspergillus oryzae

Fungal Biology, 126, 149-161 (2022)


22. Y. Higuchi*, K. Kitamoto

Traditional and latest researches on Aspergillus oryzae and related Koji molds

Journal of Fungi, 7, 1075 (2021)


21. Y. Morita, Y. Katakura, K. Takegawa, Y. Higuchi*

Correlative localization analysis between mRNA and EGFP-fused protein by single-molecule FISH using an egfp probe in Aspergillus oryzae

Frontiers in Fungal Biology, 2, 721398 (2021)


20. Y. Higuchi

Membrane traffic in Aspergillus oryzae and related filamentous fungi

Journal of Fungi, 7, 534 (2021b)


19. Y. Higuchi

Membrane traffic related to endosome dynamics and protein secretion in filamentous fungi

Bioscience, Biotechnology, and Biochemistry, 85, 1038-1045 (2021a)


18. Y. Higuchi*, K. Takegawa

Single-molecule FISH reveals subcellular localization of α-amylase and actin mRNAs in the filamentous fungus Aspergillus oryzae

Frontiers in Microbiology, 11, 578862 (2020)


17. Y. Morita, F. Kikumatsu, Y. Higuchi*, Y. Katakura, K. Takegawa

Characterization and functional analysis of ERAD-related AAA+ ATPase Cdc48 in Aspergillus oryzae

Fungal Biology, 124, 801-813 (2020)


16. Q. Li, Y. Higuchi*, K. Tanabe, Y. Katakura, K. Takegawa

Secretory production of N-glycan-deleted glycoprotein in Aspergillus oryzae

Journal of Bioscience and Bioengineering, 129, 573-580 (2020)


15. Y. Togo, Y. Higuchi*, Y. Katakura, K. Takegawa

Early endosome motility mediates α-amylase production and cell differentiation in Aspergillus oryzae

Scientific Reports, 7, 15757 (2017)


14. H.S. Kwon, K. Kawaguchi, T. Kikuma, K. Takegawa, K. Kitamoto*, Y. Higuchi*

Analysis of an acyl-CoA binding protein in Aspergillus oryzae that undergoes unconventional secretion

Biochemical and Biophysical Research Communications, 493, 481-486 (2017)


13. K. Kawaguchi, T. Kikuma, Y. Higuchi*, K. Takegawa, K. Kitamoto*

Subcellular localization of acyl-CoA binding protein in Aspergillus oryzae is regulated by autophagy machinery

Biochemical and Biophysical Research Communications, 480, 8-12 (2016)


12. M. Schuster, M. Martin-Urdiroz, Y. Higuchi, C. Hacker, S. Kilaru, S. Gurr, G. Steinberg

Co-delivery of cell wall-forming enzymes in the same vesicle for coordinated fungal cell wall formation

Nature Microbiology, 1:16149 (2016)


11. Y. Higuchi

Initial fungal effector production is mediated by early endosome motility

Communicative and Integrative Biology, 8, e1025187 (2015)


10. Y. Higuchi*, G. Steinberg*

Early endosomes motility in filamentous fungi: How and why they move

Fungal Biology Reviews, 29, 1-6 (2015)


9. E. Bielska#, Y. Higuchi#, M. Schuster#, N. Steinberg, S. Kilaru, N.J. Talbot, G. Steinberg

Long-distance endosome traffiking drives fungal effector production during plant infection

Nature Communications, 5, 5097 (2014) #These authors contributed equally.


8. Y. Higuchi, P. Ashwin, Y. Roger, G. Steinberg

Early endosome motility spatially organizes polysome distribution

Journal of Cell Biology, 204, 343-357 (2014)


7. K. Matsuo, Y. Higuchi, T. Kikuma, M. Arioka, K. Kitamoto

Functional analysis of Abp1p-interacting proteins involved in endocytosis of the MCC component in Aspergillus oryzae

Fungal Genetics and Biology, 56, 125-134 (2013)


6. Y. Higuchi, M. Arioka, K. Kitamoto

Functional analysis of the putative AAA ATPase AipA localizing at the endocytic sites in the filamentous fungus Aspergillus oryzae

FEMS Microbiology Letters, 320, 63-71 (2011)


5. K. Takaya, Y. Higuchi, K. Kitamoto, M. Arioka

A cytosolic phospholipase A2-like protein in the filamentous fungus Aspergillus oryzae localizes to the intramembrane space of the mitochondria

FEMS Microbiology Letters, 301, 201-209 (2009)


4. Y. Higuchi, M. Arioka, K. Kitamoto

Endocytic recycling at the tip region in the filamentous fungus Aspergillus oryzae

Communicative and Integrative Biology, 2, 327-328 (2009b)


3. Y. Higuchi, J.Y. Shoji, M. Arioka, K. Kitamoto

Endocytosis is crucial for cell polarity and apical membrane recycling in the filamentous fungus Aspergillus oryzae

Eukaryotic Cell, 8, 37-46 (2009a)


2. R. Hatakeyama, T. Nakahama, Y. Higuchi, K. Kitamoto

Light represses conidiation in koji mold Aspergillus oryzae

Bioscience, Biotechnology, and Biochemistry, 71, 1844-1849 (2007)


1. Y. Higuchi, T. Nakahama, J.Y. Shoji, M. Arioka, K. Kitamoto

Visualization of the endocytic pathway in the filamentous fungus Aspergillus oryzae using an EGFP-fused plasma membrane protein

Biochemical and Biophysical Research Communications, 340, 784-791 (2006)




総説・著書・報告


7. 樋口裕次郎、守田湧貴、竹川薫

Visualization of mRNA encoding glucoamylase via MS2 system in Aspergillus oryzae

九州大学 中央分析センター報告、40、23-28 (2022)


6. 樋口裕次郎

麹菌における有用物質生産に関する分子細胞生物学的解析

発酵・醸造食品の最前線II、シーエムシー出版、42-49 (2022)


5. 樋口裕次郎

糸状菌における初期エンドソーム動態の生理的意義

バイオサイエンスとインダストリー、76、218-221 (2018)


4. 樋口裕次郎

ダイナミックなオルガネラ:初期エンドソーム

日本生物工学会誌、96、79 (2018)


3. 樋口裕次郎、北本勝ひこ

麹菌のタンパク質分泌経路とエンドサイトーシス

発酵・醸造食品の最新技術と機能性II、シーエムシー出版、78-85 (2011)


2. 正路淳也、樋口裕次郎、丸山潤一、北本勝ひこ

糸状菌オルガネラの形態とその極性依存的な配置

蛋白質核酸酵素、53、753-759 (2008)


1. 正路淳也、樋口裕次郎、丸山潤一

麹菌を用いた糸状菌細胞生物学の進展

日本生物工学会誌、84、364-366 (2006)