研究業績

2023年

1. Refai MY, Elazzazy AM, Desouky SE, Abu-Elghait M, Fayed EA, Alajel SM, Alajlan AA, Albureikan MO, Nakayama J. Interception of Epoxide ring to quorum sensing system in Enterococcus faecalis and Staphylococcus aureus. AMB Express. 2023 Nov 9;13(1):126. doi: 10.1186/s13568-023-01633-9. PMID: 37946062; PMCID: PMC10636001.
2. Oshiro M, Zendo T, Tashiro Y, Nakayama J. Cyclic pairwise interaction representing a rock-paper-scissors game maintains the population of the vulnerable yeast Saccharomyces cerevisiae within a multispecies sourdough microbiome. Microbiol Spectr. 2023 Dec 12;11(6):e0137023. doi: 10.1128/spectrum.01370-23. Epub 2023 Nov 2. PMID: 37916803; PMCID: PMC10714952.
3. Mishima R, Tanaka M, Momoda R, Sanefuji M, Morokuma S, Ogawa M, Kato K, Nakayama J. Longitudinal gut mycobiota changes in Japanese infants during first three years of life. J Biosci Bioeng. 2023 Apr;135(4):266-273. doi: 10.1016/j.jbiosc.2023.01.007. Epub 2023 Feb 4. PMID: 36740519.
4. Maky MA, Zendo T. Identification of a Novel Bioactive Peptide Derived from Frozen Chicken Breast Hydrolysate and the Utilization of Hydrolysates as Biopreservatives. Biology (Basel). 2023 Sep 8;12(9):1218. doi: 10.3390/biology12091218. PMID: 37759617; PMCID: PMC10525312.

2022年

1. Perez RH, Zendo T, Sonomoto K. Multiple bacteriocin production in lactic acid bacteria. J Biosci Bioeng. 2022 Oct;134(4):277-287. doi: 10.1016/j.jbiosc.2022.07.007. Epub 2022 Aug 1. PMID: 35927130.
2. Daba GM, Mostafa FA, Saleh SAA, Elkhateeb WA, Awad G, Nomiyama T, Zendo T, El-Dein AN. Purification, amino acid sequence, and characterization of bacteriocin GA15, a novel class IIa bacteriocin secreted by Lactiplantibacillus plantarum GCNRC_GA15. Int J Biol Macromol. 2022 Jul 31;213:651-662. doi: 10.1016/j.ijbiomac.2022.06.003. Epub 2022 Jun 3. PMID: 35667456.
3. Kawahara A, Zendo T, Matsusaki H. Identification and characterization of bacteriocin biosynthetic gene clusters found in multiple bacteriocins producing Lactiplantibacillus plantarum PUK6. J Biosci Bioeng. 2022 May;133(5):444-451. doi: 10.1016/j.jbiosc.2022.01.008. Epub 2022 Feb 6. PMID: 35140055.
4. Nagao JI, Kishikawa S, Tanaka H, Toyonaga K, Narita Y, Negoro-Yasumatsu K, Tasaki S, Arita-Morioka KI, Nakayama J, Tanaka Y. Pathobiont-responsive Th17 cells in gut-mouth axis provoke inflammatory oral disease and are modulated by intestinal microbiome. Cell Rep. 2022 Sep 6;40(10):111314. doi: 10.1016/j.celrep.2022.111314. PMID: 36070692.
5. Ikari K, Tezuka J, Sanefuji M, Nakayama J, Nishima D, Sonoda Y, Ogawa M, Shimono M, Suga R, Honjo S, Kusuhara K, Ohga S; Japan Environment and Children’s Study (JECS) Group. The association between early formula and reduced risk of cow's milk allergy during the first three year of life: a Japanese cohort study. Allergy Asthma Clin Immunol. 2022 Aug 7;18(1):71. doi: 10.1186/s13223-022-00712-z. PMID: 35934704; PMCID: PMC9358901.
6. Therdtatha P, Shinoda A, Nakayama J. Crisis of the Asian gut: associations among diet, microbiota, and metabolic diseases. Biosci Microbiota Food Health. 2022;41(3):83-93. doi: 10.12938/bmfh.2021-085. Epub 2022 Feb 9. PMID: 35854695; PMCID: PMC9246424.
7. Dai H, Otsuka A, Tanabe K, Yanagita T, Nakayama J, Kitagaki H. Glucosylceramide Changes Bacterial Metabolism and Increases Gram-Positive Bacteria through Tolerance to Secondary Bile Acids In Vitro. Int J Mol Sci. 2022 May 10;23(10):5300. doi: 10.3390/ijms23105300. PMID: 35628110; PMCID: PMC9141989.
8. Desouky SE, Abu-Elghait M, Fayed EA, Selim S, Yousuf B, Igarashi Y, Abdel- Wahab BA, Mohammed Alsuhaibani A, Sonomoto K, Nakayama J. Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study. Metabolites. 2022 Mar 15;12(3):246. doi: 10.3390/metabo12030246. PMID: 35323689; PMCID: PMC8955454.
9. Tourlousse DM, Narita K, Miura T, Ohashi A, Matsuda M, Ohyama Y, Shimamura M, Furukawa M, Kasahara K, Kameyama K, Saito S, Goto M, Shimizu R, Mishima R, Nakayama J, Hosomi K, Kunisawa J, Terauchi J, Sekiguchi Y, Kawasaki H. Characterization and Demonstration of Mock Communities as Control Reagents for Accurate Human Microbiome Community Measurements. Microbiol Spectr. 2022 Mar 2;10(2):e0191521. doi: 10.1128/spectrum.01915-21. Epub ahead of print. PMID: 35234490; PMCID: PMC8941912.
10. Phoonlapdacha P, Tangshewinsirikul C, Phosuwattanakul J, Kittisakmontri K, Nitisinprasert S, Nakayama J, Prombutara P, Suthutvoravut U, Chongviriyaphan N. Gut microbiome profiles in Thai healthy pregnant women and its association with types of foods. BMC Pregnancy Childbirth. 2022 Jan 29;22(1):79. doi: 10.1186/s12884-022-04397-5. PMID: 35093031; PMCID: PMC8801080.

2021年

1. Ishibashi N, Matsumoto N, Perez RH, Iwatani S, Sugino H, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Molecular characterization of the possible regulation of multiple bacteriocin production through a three-component regulatory system in Enterococcus faecium NKR-5-3. J Biosci Bioeng. 2020 Oct 21:S1389-1723(20)30368-6. doi: 10.1016/j.jbiosc.2020.09.019.PMID: 34756351.
2. Watanabe M, Sianoya A, Mishima R, Therdtatha P, Rodriguez A, Ramos DC, Lee YK, Dalmacio LM, Nakayama J. Gut microbiome status of urban and rural Filipino adults in relation to diet and metabolic disorders. FEMS Microbiol Lett. 2021 Dec 7;368(20):fnab149. doi: 10.1093/femsle/fnab149. PMID: 34849762.
3. Oshiro M, Tanaka M, Momoda R, Zendo T, Nakayama J. Mechanistic Insight into Yeast Bloom in a Lactic Acid Bacteria Relaying-Community in the Start of Sourdough Microbiota Evolution. Microbiol Spectr. 2021 Oct 31;9(2):e0066221. doi: 10.1128/Spectrum.00662-21. Epub 2021 Oct 20. PMID: 34668750; PMCID: PMC8528097.
4. Maky MA, Ishibashi N, Nakayama J, Zendo T. Characterization of the Biosynthetic Gene Cluster of Enterocin F4-9, a Glycosylated Bacteriocin. Microorganisms. 2021 Nov 1;9(11):2276. doi: 10.3390/microorganisms9112276. PMID: 34835402; PMCID: PMC8620827.
5. Onizuka S, Tanaka M, Mishima R, Nakayama J. Cultivation of Spore-Forming Gut Microbes Using a Combination of Bile Acids and Amino Acids. Microorganisms. 2021 Aug 2;9(8):1651. doi: 10.3390/microorganisms9081651. PMID: 34442730; PMCID: PMC8401671.
6. Inoue T, Funatsu Y, Ohnishi M, Isogawa M, Kawashima K, Tanaka M, Moriya K, Kawaratani H, Momoda R, Iio E, Nakagawa H, Suzuki Y, Matsuura K, Fujiwara K, Nakajima A, Yoshiji H, Nakayama J, Tanaka Y. Bile acid dysmetabolism in the gut- microbiota-liver axis under hepatitis C virus infection. Liver Int. 2022 Jan;42(1):124-134. doi: 10.1111/liv.15041. Epub 2021 Sep 5. PMID: 34411400.
7. Nishihara Y, Ogino H, Tanaka M, Ihara E, Fukaura K, Nishioka K, Chinen T, Tanaka Y, Nakayama J, Kang D, Ogawa Y. Mucosa-associated gut microbiota reflects clinical course of ulcerative colitis. Sci Rep. 2021 Jul 2;11(1):13743. doi: 10.1038/s41598-021-92870-0. PMID: 34215773; PMCID: PMC8253849.
8. Therdtatha P, Song Y, Tanaka M, Mariyatun M, Almunifah M, Manurung NEP, Indriarsih S, Lu Y, Nagata K, Fukami K, Ikeda T, Lee YK, Rahayu ES, Nakayama J. Gut Microbiome of Indonesian Adults Associated with Obesity and Type 2 Diabetes: A Cross-Sectional Study in an Asian City, Yogyakarta. Microorganisms. 2021 Apr 22;9(5):897. doi: 10.3390/microorganisms9050897. PMID: 33922321; PMCID: PMC8147061.
9. Kamil RZ, Murdiati A, Juffrie M, Nakayama J, Rahayu ES. Gut Microbiota and Short-Chain Fatty Acid Profile between Normal and Moderate Malnutrition Children in Yogyakarta, Indonesia. Microorganisms. 2021 Jan 7;9(1):127. doi: 10.3390/microorganisms9010127. PMID: 33430510; PMCID: PMC7826765.
10. Chumponsuk T, Gruneck L, Gentekaki E, Jitprasertwong P, Kullawong N, Nakayama J, Popluechai S. The salivary microbiota of Thai adults with metabolic disorders and association with diet. Arch Oral Biol. 2021 Feb;122:105036. doi: 10.1016/j.archoralbio.2020.105036. Epub 2021 Jan 2. PMID: 33421657.
11. Oshiro M, Zendo T, Nakayama J. Diversity and dynamics of sourdough lactic acid bacteriota created by a slow food fermentation system. J Biosci Bioeng. 2021 Apr;131(4):333-340. doi: 10.1016/j.jbiosc.2020.11.007. Epub 2021 Jan 6. PMID: 33358094.

2020年

1. Ishibashi N, Matsumoto N, Perez RH, Iwatani S, Sugino H, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Molecular characterization of the possible regulation of multiple bacteriocin production through a three-component regulatory system in Enterococcus faecium NKR-5-3. J Biosci Bioeng. 2020 Oct 21:S1389-1723(20)30368-6. doi: 10.1016/j.jbiosc.2020.09.019. Epub ahead of print. PMID: 34756351.
2. Tanaka M, Onizuka S, Mishima R, Nakayama J. Cultural isolation of spore- forming bacteria in human feces using bile acids. Sci Rep. 2020 Sep 14;10(1):15041. doi: 10.1038/s41598-020-71883-1. PMID: 32929101; PMCID: PMC7490687.
3. Sushida H, Sakei M, Perez RH, Ishibashi N, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Processing and secretion of non- cognate bacteriocins by EnkT, an ABC transporter from a multiple-bacteriocin producer, Enterococcus faecium NKR-5-3. J Biosci Bioeng. 2020 Dec;130(6):596-603. doi: 10.1016/j.jbiosc.2020.07.017. Epub 2020 Aug 24. PMID: 32855046.
4. Oshiro M, Tanaka M, Zendo T, Nakayama J. Impact of pH on succession of sourdough lactic acid bacteria communities and their fermentation properties. Biosci Microbiota Food Health. 2020;39(3):152-159. doi: 10.12938/bmfh.2019-038. Epub 2020 Mar 6. PMID: 32775134; PMCID: PMC7392915.
5. La-Ongkham O, Nakphaichit M, Nakayama J, Keawsompong S, Nitisinprasert S. Age-related changes in the gut microbiota and the core gut microbiome of healthy Thai humans. 3 Biotech. 2020 Jun;10(6):276. doi: 10.1007/s13205-020-02265-7. Epub 2020 May 30. PMID: 32537376; PMCID: PMC7261292.
6. Khine WWT, Rahayu ES, See TY, Kuah S, Salminen S, Nakayama J, Lee YK. Indonesian children fecal microbiome from birth until weaning was different from microbiomes of their mothers. Gut Microbes. 2020 Nov 9;12(1):1761240. doi: 10.1080/19490976.2020.1761240. Epub 2020 May 26. PMID: 32453977; PMCID: PMC7524161.
7. Ikeda T, Aida M, Yoshida Y, Matsumoto S, Tanaka M, Nakayama J, Nagao Y, Nakata R, Oki E, Akahoshi T, Okano S, Nomura M, Hashizume M, Maehara Y. Alteration in faecal bile acids, gut microbial composition and diversity after laparoscopic sleeve gastrectomy. Br J Surg. 2020 Nov;107(12):1673-1685. doi: 10.1002/bjs.11654. Epub 2020 May 20. PMID: 32432347.
8. Furukawa M, Moriya K, Nakayama J, Inoue T, Momoda R, Kawaratani H, Namisaki T, Sato S, Douhara A, Kaji K, Kitade M, Shimozato N, Sawada Y, Saikawa S, Takaya H, Kitagawa K, Akahane T, Mitoro A, Yamao J, Tanaka Y, Yoshiji H. Gut dysbiosis associated with clinical prognosis of patients with primary biliary cholangitis. Hepatol Res. 2020 Jul;50(7):840-852. doi: 10.1111/hepr.13509. Epub 2020 Jun 10. PMID: 32346970.
9. Fujiwara M, Kuwahara D, Hayashi M, Zendo T, Sato M, Nakayama J, Sonomoto K. Lowering effect of viable Pediococcus pentosaceus QU 19 on the rise in postprandial glucose. Biosci Microbiota Food Health. 2020;39(2):57-64. doi: 10.12938/bmfh.19-041. Epub 2020 Jan 25. PMID: 32328401; PMCID: PMC7162691.
10. Fukao M, Zendo T, Inoue T, Fuke N, Moriuchi T, Yamane Y, Nakayama J, Sonomoto K, Fukaya T. Relation between cell-bound exopolysaccharide production via plasmid-encoded genes and rugose colony morphology in the probiotic Lactobacillus brevis KB290. Anim Sci J. 2019 Dec;90(12):1575-1580. doi: 10.1111/asj.13297. Epub 2019 Oct 8. PMID: 31593351.
11. Tanaka M, Sanefuji M, Morokuma S, Yoden M, Momoda R, Sonomoto K, Ogawa M, Kato K, Nakayama J. The association between gut microbiota development and maturation of intestinal bile acid metabolism in the first 3 y of healthy Japanese infants. Gut Microbes. 2020;11(2):205-216. doi: 10.1080/19490976.2019.1650997. Epub 2019 Sep 24. PMID: 31550982; PMCID: PMC7053967.
12. Fukao M, Zendo T, Inoue T, Nakayama J, Suzuki S, Fukaya T, Yajima N, Sonomoto K. Plasmid-encoded glycosyltransferase operon is responsible for exopolysaccharide production, cell aggregation, and bile resistance in a probiotic strain, Lactobacillus brevis KB290. J Biosci Bioeng. 2019 Oct;128(4):391-397. doi: 10.1016/j.jbiosc.2019.04.008. Epub 2019 May 22. PMID: 31126721.
13. Littlewood S, Tattersall H, Hughes CS, Hussain R, Ma P, Harding SE, Nakayama J, Phillips-Jones MK. The gelatinase biosynthesis-activating pheromone binds and stabilises the FsrB membrane protein in Enterococcus faecalis quorum sensing. FEBS Lett. 2020 Feb;594(3):553-563. doi: 10.1002/1873-3468.13634. Epub 2019 Oct 21. PubMed PMID: 31598959; PubMed Central PMCID: PMC7028047.
14. Tanaka M, Sanefuji M, Morokuma S, Yoden M, Momoda R, Sonomoto K, Ogawa M, Kato K, Nakayama J. The association between gut microbiota development and maturation of intestinal bile acid metabolism in the first 3 y of healthy Japanese infants. Gut Microbes. 2020;11(2):205-216. doi: 10.1080/19490976.2019.1650997. Epub 2019 Sep 24. PubMed PMID: 31550982; PubMed Central PMCID: PMC7053967.

2019年

1. Fukao M, Zendo T, Inoue T, Fuke N, Moriuchi T, Yamane Y, Nakayama J, Sonomoto K, Fukaya T. Relation between cell-bound exopolysaccharide production via plasmid-encoded genes and rugose colony morphology in the probiotic Lactobacillus brevis KB290. Anim Sci J. 2019 Dec;90(12):1575-1580. doi: 10.1111/asj.13297. Epub 2019 Oct 8. PubMed PMID: 31593351.
2. Fukao M, Zendo T, Inoue T, Nakayama J, Suzuki S, Fukaya T, Yajima N, Sonomoto K. Plasmid-encoded glycosyltransferase operon is responsible for exopolysaccharide production, cell aggregation, and bile resistance in a probiotic strain, Lactobacillus brevis KB290. J Biosci Bioeng. 2019 Oct;128(4):391-397. doi: 10.1016/j.jbiosc.2019.04.008. Epub 2019 May 22. PubMed PMID: 31126721.
3. Hamajima H, Tanaka M, Miyagawa M, Sakamoto M, Nakamura T, Yanagita T, Nishimukai M, Mitsutake S, Nakayama J, Nagao K, Kitagaki H. Koji glycosylceramide commonly contained in Japanese traditional fermented foods alters cholesterol metabolism in obese mice. Biosci Biotechnol Biochem. 2019 Aug;83(8):1514-1522. doi: 10.1080/09168451.2018.1562877. Epub 2018 Dec 30. PubMed PMID: 30595103.
4. Oshiro M, Momoda R, Tanaka M, Zendo T, Nakayama J. Dense tracking of the dynamics of the microbial community and chemicals constituents in spontaneous wheat sourdough during two months of backslopping. J Biosci Bioeng. 2019 Aug;128(2):170-176. doi: 10.1016/j.jbiosc.2019.02.006. Epub 2019 Mar 14. PubMed PMID: 30879925.

2018年

1. Inoue T, Nakayama J, Moriya K, Kawaratani H, Momoda R, Ito K, Iio E, Nojiri S, Fujiwara K, Yoneda M, Yoshiji H, Tanaka Y. Gut Dysbiosis Associated With Hepatitis C Virus Infection. Clin Infect Dis. 2018 Aug 31;67(6):869-877. doi: 10.1093/cid/ciy205. PubMed PMID: 29718124.
2. Sushida H, Ishibashi N, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Evaluation of leader peptides that affect the secretory ability of a multiple bacteriocin transporter, EnkT. J Biosci Bioeng. 2018 Jul;126(1):23-29. doi: 10.1016/j.jbiosc.2018.01.015. Epub 2018 Feb 13. PubMed PMID: 29452934.
3. Kisuse J, La-Ongkham O, Nakphaichit M, Therdtatha P, Momoda R, Tanaka M, Fukuda S, Popluechai S, Kespechara K, Sonomoto K, Lee YK, Nitisinprasert S, Nakayama J. Urban Diets Linked to Gut Microbiome and Metabolome Alterations in Children: A Comparative Cross-Sectional Study in Thailand. Front Microbiol. 2018 Jun 22;9:1345. doi: 10.3389/fmicb.2018.01345. eCollection 2018. PubMed PMID: 29988433; PubMed Central PMCID: PMC6024022.
4. Adachi K, Ohtani K, Kawano M, Singh RP, Yousuf B, Sonomoto K, Shimizu T, Nakayama J. Metabolic dependent and independent pH-drop shuts down VirSR quorum sensing in Clostridium perfringens. J Biosci Bioeng. 2018 May;125(5):525-531. doi: 10.1016/j.jbiosc.2017.12.019. Epub 2018 Jan 17. PubMed PMID: 29373309.

2017年

1. Tanaka M, Nakayama J. Development of the gut microbiota in infancy and its impact on health in later life. Allergol Int. 2017 Oct;66(4):515-522. doi: 10.1016/j.alit.2017.07.010. Epub 2017 Aug 18. Review. PubMed PMID: 28826938.
2. Kitazaki K, Koga S, Nagatoshi K, Kuwano K, Zendo T, Nakayama J, Sonomoto K, Ano H, Katamoto H. In vitro synergistic activities of cefazolin and nisin A against mastitis pathogens. J Vet Med Sci. 2017 Sep 12;79(9):1472-1479. doi: 10.1292/jvms.17-0180. Epub 2017 Jul 29. PubMed PMID: 28757508; PubMed Central PMCID: PMC5627315.
3. Tanaka M, Korenori Y, Washio M, Kobayashi T, Momoda R, Kiyohara C, Kuroda A, Saito Y, Sonomoto K, Nakayama J. Signatures in the gut microbiota of Japanese infants who developed food allergies in early childhood. FEMS Microbiol Ecol. 2017 Aug 1;93(8). doi: 10.1093/femsec/fix099. PubMed PMID: 28903469.
4. Perez RH, Sugino H, Ishibashi N, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Mutations near the cleavage site of enterocin NKR-5-3B prepeptide reveal new insights into its biosynthesis. Microbiology. 2017 Apr;163(4):431-441. doi: 10.1099/mic.0.000435. Epub 2017 Apr 12. PubMed PMID: 28113050.
5. Nakayama J, Yamamoto A, Palermo-Conde LA, Higashi K, Sonomoto K, Tan J, Lee YK. Impact of Westernized Diet on Gut Microbiota in Children on Leyte Island. Front Microbiol. 2017 Feb 14;8:197. doi: 10.3389/fmicb.2017.00197. eCollection 2017. PubMed PMID: 28261164; PubMed Central PMCID: PMC5306386.
6. Fujita Y, Tsuno H, Nakayama J. Fermented Papaya Preparation Restores Age-Related Reductions in Peripheral Blood Mononuclear Cell Cytolytic Activity in Tube-Fed Patients. PLoS One. 2017 Jan 6;12(1):e0169240. doi: 10.1371/journal.pone.0169240. eCollection 2017. PubMed PMID: 28060858; PubMed Central PMCID: PMC5218495.

2016年

1. Ruengsomwong S, La-Ongkham O, Jiang J, Wannissorn B, Nakayama J, Nitisinprasert S. Microbial Community of Healthy Thai Vegetarians and Non-Vegetarians, Their Core Gut Microbiota, and Pathogen Risk. J Microbiol Biotechnol. 2016 Oct 28;26(10):1723-1735. doi: 10.4014/jmb.1603.03057. PubMed PMID: 27381339.
2. Iwatani S, Ishibashi N, Flores FP, Zendo T, Nakayama J, Sonomoto K. LnqR, a TetR-family transcriptional regulator, positively regulates lacticin Q production in Lactococcus lactis QU 5. FEMS Microbiol Lett. 2016 Sep;363(18). pii: fnw200. doi: 10.1093/femsle/fnw200. Epub 2016 Aug 21. PubMed PMID: 27549303.
3. Hamajima H, Matsunaga H, Fujikawa A, Sato T, Mitsutake S, Yanagita T, Nagao K, Nakayama J, Kitagaki H. Japanese traditional dietary fungus koji Aspergillus oryzae functions as a prebiotic for Blautia coccoides through glycosylceramide: Japanese dietary fungus koji is a new prebiotic. Springerplus. 2016 Aug 11;5(1):1321. doi: 10.1186/s40064-016-2950-6. eCollection 2016. Erratum in: Springerplus. 2016 Oct 25;5(1):1869. PubMed PMID: 27563516; PubMed Central PMCID: PMC4980852.
4. Terahara T, Yamada K, Nakayama J, Igarashi Y, Kobayashi T, Imada C. Bacterial community structures of deep-sea water investigated by molecular biological techniques. Gene. 2016 Feb 1;576(2 Pt 1):696-700. doi: 10.1016/j.gene.2015.10.027. Epub 2015 Oct 22. PubMed PMID: 26475936.
5. Singh RP, Desouky SE, Nakayama J. Quorum Quenching Strategy Targeting Gram-Positive Pathogenic Bacteria. Adv Exp Med Biol. 2016;901:109-30. doi: 10.1007/5584_2016_1. Review. PubMed PMID: 27167409.
6. Perez RH, Ishibashi N, Inoue T, Himeno K, Masuda Y, Sawa N, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Functional Analysis of Genes Involved in the Biosynthesis of Enterocin NKR-5-3B, a Novel Circular Bacteriocin. J Bacteriol. 2015 Oct 26;198(2):291-300. doi: 10.1128/JB.00692-15. Print 2016 Jan 15. PubMed PMID: 26503847; PubMed Central PMCID: PMC4751792.

2015年

1. Shimafuji C, Noguchi M, Nishie M, Nagao J, Shioya K, Zendo T, Nakayama J, Sonomoto K. In vitro catalytic activity of N-terminal and C-terminal domains in NukM, the post-translational modification enzyme of nukacin ISK-1. J Biosci Bioeng. 2015 Dec;120(6):624-9. doi: 10.1016/j.jbiosc.2015.03.020. Epub 2015 May 9. PubMed PMID: 25971839.
2. Igarashi Y, Yamamoto K, Fukuda T, Shojima A, Nakayama J, Carro L, Trujillo ME. Arthroamide, a Cyclic Depsipeptide with Quorum Sensing Inhibitory Activity from Arthrobacter sp. J Nat Prod. 2015 Nov 25;78(11):2827-31. doi: 10.1021/acs.jnatprod.5b00540. Epub 2015 Nov 17. PubMed PMID: 26575343.
3. Toh H, Morita H, Tsuji H, Iwashita K, Goto N, Nakayama J, Sekine M, Kato Y, Suzuki K, Fujita N. Complete genome sequence of Lactobacillus acetotolerans RIB 9124 (NBRC 13120) isolated from putrefied (hiochi) Japanese sake. J Biotechnol. 2015 Nov 20;214:214-5. doi: 10.1016/j.jbiotec.2015.09.006. Epub 2015 Sep 12. PubMed PMID: 26376472.
4. Singh RP, Okubo K, Ohtani K, Adachi K, Sonomoto K, Nakayama J. Rationale design of quorum-quenching peptides that target the VirSR system of Clostridium perfringens. FEMS Microbiol Lett. 2015 Nov;362(22). pii: fnv188. doi: 10.1093/femsle/fnv188. Epub 2015 Oct 5. PubMed PMID: 26443835.
5. Igarashi Y, Gohda F, Kadoshima T, Fukuda T, Hanafusa T, Shojima A, Nakayama J, Bills GF, Peterson S. Avellanin C, an inhibitor of quorum-sensing signaling in Staphylococcus aureus, from Hamigera ingelheimensis. J Antibiot (Tokyo). 2015 Nov;68(11):707-10. doi: 10.1038/ja.2015.50. Epub 2015 May 6. PubMed PMID: 25944536.
6. Perez RH, Ishibashi N, Inoue T, Himeno K, Masuda Y, Sawa N, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Functional Analysis of Genes Involved in the Biosynthesis of Enterocin NKR-5-3B, a Novel Circular Bacteriocin. J Bacteriol. 2015 Oct 26;198(2):291-300. doi: 10.1128/JB.00692-15. Print 2016 Jan 15. PubMed PMID: 26503847; PubMed Central PMCID: PMC4751792.
7. Himeno K, Rosengren KJ, Inoue T, Perez RH, Colgrave ML, Lee HS, Chan LY, Henriques ST, Fujita K, Ishibashi N, Zendo T, Wilaipun P, Nakayama J, Leelawatcharamas V, Jikuya H, Craik DJ, Sonomoto K. Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium. Biochemistry. 2015 Aug 11;54(31):4863-76. doi: 10.1021/acs.biochem.5b00196. Epub 2015 Jul 31. PubMed PMID: 26174911.
8. Desouky SE, Shojima A, Singh RP, Matsufuji T, Igarashi Y, Suzuki T, Yamagaki T, Okubo K, Ohtani K, Sonomoto K, Nakayama J. Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria. FEMS Microbiol Lett. 2015 Jul;362(14). pii: fnv109. doi: 10.1093/femsle/fnv109. Epub 2015 Jul 5. PubMed PMID: 26149266.
9. Nakayama J, Watanabe K, Jiang J, Matsuda K, Chao SH, Haryono P, La-Ongkham O, Sarwoko MA, Sujaya IN, Zhao L, Chen KT, Chen YP, Chiu HH, Hidaka T, Huang NX, Kiyohara C, Kurakawa T, Sakamoto N, Sonomoto K, Tashiro K, Tsuji H, Chen MJ, Leelavatcharamas V, Liao CC, Nitisinprasert S, Rahayu ES, Ren FZ, Tsai YC, Lee YK. Diversity in gut bacterial community of school-age children in Asia. Sci Rep. 2015 Feb 23;5:8397. doi: 10.1038/srep08397. Erratum in: Sci Rep. 2019 Apr 25;9(1):6530. PubMed PMID: 25703686; PubMed Central PMCID: PMC4336934.
10. Ono H, Nishio S, Tsurii J, Kawamoto T, Sonomoto K, Nakayama J. Effects of Japanese pepper and red pepper on the microbial community during nukadoko fermentation. Biosci Microbiota Food Health. 2015;34(1):1-9. doi: 10.12938/bmfh.2014-011. Epub 2014 Sep 27. PubMed PMID: 25625032; PubMed Central PMCID: PMC4300311.

2014年

1. Enomoto T, Sowa M, Nishimori K, Shimazu S, Yoshida A, Yamada K, Furukawa F, Nakagawa T, Yanagisawa N, Iwabuchi N, Odamaki T, Abe F, Nakayama J, Xiao JZ. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int. 2014 Dec;63(4):575-85. doi: 10.2332/allergolint.13-OA-0683. Epub 2014 Jul 25. PubMed PMID: 25056226.
2. Ishibashi N, Himeno K, Masuda Y, Perez RH, Iwatani S, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Gene cluster responsible for secretion of and immunity to multiple bacteriocins, the NKR-5-3 enterocins. Appl Environ Microbiol. 2014 Nov;80(21):6647-55. doi: 10.1128/AEM.02312-14. Epub 2014 Aug 22. PubMed PMID: 25149515; PubMed Central PMCID: PMC4249031.
3. Ono H, Nishio S, Tsurii J, Kawamoto T, Sonomoto K, Nakayama J. Monitoring of the microbiota profile in nukadoko, a naturally fermented rice bran bed for pickling vegetables. J Biosci Bioeng. 2014 Nov;118(5):520-5. doi: 10.1016/j.jbiosc.2014.04.017. Epub 2014 Jun 3. PubMed PMID: 24906947.
4. Ruengsomwong S, Korenori Y, Sakamoto N, Wannissorn B, Nakayama J, Nitisinprasert S. Senior Thai fecal microbiota comparison between vegetarians and non-vegetarians using PCR-DGGE and real-time PCR. J Microbiol Biotechnol. 2014 Aug;24(8):1026-33. PubMed PMID: 24743571.
5. Kato K, Toh H, Sakamoto N, Mori K, Tashiro K, Hibi N, Sonomoto K, Nakayama J. Draft Genome Sequence of Lactobacillus namurensis Chizuka 01, Isolated from Nukadoko, a Pickling Bed of Fermented Rice Bran. Genome Announc. 2014 Feb 6;2(1). pii: e01263-13. doi: 10.1128/genomeA.01263-13. PubMed PMID: 24504001; PubMed Central PMCID: PMC3916495.
6. Mu F, Masuda Y, Zendo T, Ono H, Kitagawa H, Ito H, Nakayama J, Sonomoto K. Biological function of a DUF95 superfamily protein involved in the biosynthesis of a circular bacteriocin, leucocyclicin Q. J Biosci Bioeng. 2014 Feb;117(2):158-164. doi: 10.1016/j.jbiosc.2013.06.023. Epub 2013 Jul 29. PubMed PMID: 23906710.
7. Shojima A, Nakayama J. Quorum sensing in gram-positive bacteria: assay protocols for staphylococcal agr and enterococcal fsr systems. Methods Mol Biol. 2014;1147:33-41. doi: 10.1007/978-1-4939-0467-9_3. PubMed PMID: 24664824.

2013年

1. Li M, Yoneyama F, Toshimitsu N, Zendo T, Nakayama J, Sonomoto K. Lethal hydroxyl radical accumulation by a lactococcal bacteriocin, lacticin Q. Antimicrob Agents Chemother. 2013 Aug;57(8):3897-902. doi: 10.1128/AAC.00638-13. Epub 2013 Jun 3. PubMed PMID: 23733459; PubMed Central PMCID: PMC3719721.
2. Teixeira N, Varahan S, Gorman MJ, Palmer KL, Zaidman-Remy A, Yokohata R, Nakayama J, Hancock LE, Jacinto A, Gilmore MS, de Fatima Silva Lopes M. Drosophila host model reveals new enterococcus faecalis quorum-sensing associated virulence factors. PLoS One. 2013 May 29;8(5):e64740. doi: 10.1371/journal.pone.0064740. Print 2013. PubMed PMID: 23734216; PubMed Central PMCID: PMC3667150.
3. Nakayama J, Yokohata R, Sato M, Suzuki T, Matsufuji T, Nishiguchi K, Kawai T, Yamanaka Y, Nagata K, Tanokura M, Sonomoto K. Development of a peptide antagonist against fsr quorum sensing of Enterococcus faecalis. ACS Chem Biol. 2013 Apr 19;8(4):804-11. doi: 10.1021/cb300717f. Epub 2013 Feb 7. PubMed PMID: 23362999.
4. Iwatani S, Horikiri Y, Zendo T, Nakayama J, Sonomoto K. Bifunctional gene cluster lnqBCDEF mediates bacteriocin production and immunity with differential genetic requirements. Appl Environ Microbiol. 2013 Apr;79(7):2446-9. doi: 10.1128/AEM.03783-12. Epub 2013 Jan 18. PubMed PMID: 23335763; PubMed Central PMCID: PMC3623217.
5. Phillips-Jones MK, Patching SG, Edara S, Nakayama J, Hussain R, Siligardi G. Interactions of the intact FsrC membrane histidine kinase with the tricyclic peptide inhibitor siamycin I revealed through synchrotron radiation circular dichroism. Phys Chem Chem Phys. 2013 Jan 14;15(2):444-7. doi: 10.1039/c2cp43722h. Epub 2012 Nov 26. PubMed PMID: 23183669.
6. Desouky SE, Nishiguchi K, Zendo T, Igarashi Y, Williams P, Sonomoto K, Nakayama J. High-throughput screening of inhibitors targeting Agr/Fsr quorum sensing in Staphylococcus aureus and Enterococcus faecalis. Biosci Biotechnol Biochem. 2013;77(5):923-7. Epub 2013 May 7. PubMed PMID: 23649251.
7. Nakayama J, Jiang J, Watanabe K, Chen K, Ninxin H, Matsuda K, Kurakawa T, Tsuji H, Sonomoto K, Lee YK. Up to Species-level Community Analysis of Human Gut Microbiota by 16S rRNA Amplicon Pyrosequencing. Biosci Microbiota Food Health. 2013;32(2):69-76. doi: 10.12938/bmfh.32.69. Epub 2013 Apr 27. PubMed PMID: 24936364; PubMed Central PMCID: PMC4034321.

2012年

1. Iwatani S, Yoneyama F, Miyashita S, Zendo T, Nakayama J, Sonomoto K. Identification of the genes involved in the secretion and self-immunity of lacticin Q, an unmodified leaderless bacteriocin from Lactococcus lactis QU 5. Microbiology. 2012 Dec;158(Pt 12):2927-2935. doi: 10.1099/mic.0.062943-0. Epub 2012 Oct 25. PubMed PMID: 23103973.
2. Perez RH, Himeno K, Ishibashi N, Masuda Y, Zendo T, Fujita K, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Monitoring of the multiple bacteriocin production by Enterococcus faecium NKR-5-3 through a developed liquid chromatography and mass spectrometry-based quantification system. J Biosci Bioeng. 2012 Nov;114(5):490-6. doi: 10.1016/j.jbiosc.2012.06.003. Epub 2012 Jul 3. PubMed PMID: 22762972.
3. Patching SG, Edara S, Ma P, Nakayama J, Hussain R, Siligardi G, Phillips-Jones MK. Interactions of the intact FsrC membrane histidine kinase with its pheromone ligand GBAP revealed through synchrotron radiation circular dichroism. Biochim Biophys Acta. 2012 Jul;1818(7):1595-602. PubMed PMID: 22366202.
4. Islam MR, Nishie M, Nagao J, Zendo T, Keller S, Nakayama J, Kohda D, Sahl HG, Sonomoto K. Ring A of nukacin ISK-1: a lipid II-binding motif for type-A(II) lantibiotic. J Am Chem Soc. 2012 Feb 29;134(8):3687-90. doi: 10.1021/ja300007h. Epub 2012 Feb 17. PubMed PMID: 22329487.
5. Sawa N, Wilaipun P, Kinoshita S, Zendo T, Leelawatcharamas V, Nakayama J, Sonomoto K. Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1. Appl Environ Microbiol. 2012 Feb;78(3):900-3. doi: 10.1128/AEM.06497-11. Epub 2011 Dec 2. PubMed PMID: 22138996; PubMed Central PMCID: PMC3264125.
6. Yamamoto K, Takao T, Nakayama J, Kiuchi H, Okuda H, Fukuhara S, Yoshioka I, Matsuoka Y, Miyagawa Y, Tsujimura A, Nonomura N. Water avoidance stress induces frequency through cyclooxygenase-2 expression: a bladder rat model. Int J Urol. 2012 Feb;19(2):155-62. doi: 10.1111/j.1442-2042.2011.02905.x. Epub 2011 Dec 5. PubMed PMID: 22142485.
7. Teixeira N, Santos S, Marujo P, Yokohata R, Iyer VS, Nakayama J, Hancock LE, Serror P, Silva Lopes MF. The incongruent gelatinase genotype and phenotype in Enterococcus faecalis are due to shutting off the ability to respond to the gelatinase biosynthesis-activating pheromone (GBAP) quorum-sensing signal. Microbiology. 2012 Feb;158(Pt 2):519-528. doi: 10.1099/mic.0.055574-0. Epub 2011 Nov 24. PubMed PMID: 22117005; PubMed Central PMCID: PMC4083509.
8. Puramattathu TV, Islam MR, Nishie M, Yanagihara S, Nagao J, Okuda K, Zendo T, Nakayama J, Sonomoto K. Enhanced production of nukacin D13E in Lactococcus lactis NZ9000 by the additional expression of immunity genes. Appl Microbiol Biotechnol. 2012 Jan;93(2):671-8. doi: 10.1007/s00253-011-3563-1. Epub 2011 Sep 9. PubMed PMID: 21904816.
9. Himeno K, Fujita K, Zendo T, Wilaipun P, Ishibashi N, Masuda Y, Yoneyama F, Leelawatcharamas V, Nakayama J, Sonomoto K. Identification of enterocin NKR-5-3C, a novel class IIa bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3. Biosci Biotechnol Biochem. 2012;76(6):1245-7. Epub 2012 Jun 7. PubMed PMID: 22790957.
10. Ishibashi N, Himeno K, Fujita K, Masuda Y, Perez RH, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K. Purification and characterization of multiple bacteriocins and an inducing peptide produced by Enterococcus faecium NKR-5-3 from Thai fermented fish. Biosci Biotechnol Biochem. 2012;76(5):947-53. Epub 2012 May 7. PubMed PMID: 22738965.

2011年

1. Nakayama J, Kobayashi T, Tanaka S, Korenori Y, Tateyama A, Sakamoto N, Kiyohara C, Shirakawa T, Sonomoto K. Aberrant structures of fecal bacterial community in allergic infants profiled by 16S rRNA gene pyrosequencing. FEMS Immunol Med Microbiol. 2011 Dec;63(3):397-406. doi: 10.1111/j.1574-695X.2011.00872.x. Epub 2011 Oct 10. PubMed PMID: 22029688.
2. Yoneyama F, Ohno K, Imura Y, Li M, Zendo T, Nakayama J, Matsuzaki K, Sonomoto K. Lacticin Q-mediated selective toxicity depending on physicochemical features of membrane components. Antimicrob Agents Chemother. 2011 May;55(5):2446-50. doi: 10.1128/AAC.00808-10. Epub 2011 Jan 31. PubMed PMID: 21282423; PubMed Central PMCID: PMC3088220.
3. Nishie M, Sasaki M, Nagao J, Zendo T, Nakayama J, Sonomoto K. Lantibiotic transporter requires cooperative functioning of the peptidase domain and the ATP binding domain. J Biol Chem. 2011 Apr 1;286(13):11163-9. doi: 10.1074/jbc.M110.212704. Epub 2011 Feb 8. PubMed PMID: 21303905; PubMed Central PMCID: PMC3064170.
4. Sakamoto N, Tanaka S, Sonomoto K, Nakayama J. 16S rRNA pyrosequencing-based investigation of the bacterial community in nukadoko, a pickling bed of fermented rice bran. Int J Food Microbiol. 2011 Jan 5;144(3):352-9. doi: 10.1016/j.ijfoodmicro.2010.10.017. Epub 2010 Nov 16. PubMed PMID: 21084126.
5. Nagao J, Shioya K, Harada Y, Okuda K, Zendo T, Nakayama J, Sonomoto K. Engineering unusual amino acids into peptides using lantibiotic synthetase. Methods Mol Biol. 2011;705:225-36. doi: 10.1007/978-1-61737-967-3_13. Review. PubMed PMID: 21125389.